Vignes, Stéphane Albuisson, Juliette Champion, Laurence Constans, Joël Tauveron, Valérie Malloizel, Julie Quéré, Isabelle Simon, Laura Arrault, Maria Trévidic, Patrick
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Published in
Orphanet Journal of Rare Diseases
Primary lymphedema is a rare chronic pathology associated with constitutional abnormalities of the lymphatic system. The objective of this French National Diagnosis and Care Protocol (Protocole National de Diagnostic et de Soins; PNDS), based on a critical literature review and multidisciplinary expert consensus, is to provide health professionals ...
Martinat, Charlotte Cormier, Arthur Tobaly-Tapiero, Joëlle Palmic, Noé Casartelli, Nicoletta Mahboubi, Bijan Coggins, Si’Ana A. Buchrieser, Julian Persaud, Mirjana Diaz-Griffero, Felipe
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Published in
Nature Communications
SAMHD1 is a cellular dNTPase proposed to inhibit HIV-1 reverse transcription in non-cycling immune cells by limiting dNTP substrate supply; its anti-viral but not dNTPase function is downregulated by phosphorylation of T592. Here, Martinat et al. describe an additional SUMOylation at residue K595, which promotes the dNTPase-independent restriction ...
Martin Lorenzo, Sandra Nalesso, Valérie Chevalier, Claire Birling, Marie-Christine Herault, Yann
Published in
Molecular Autism
BackgroundGene copy number variants play an important role in the occurrence of neurodevelopmental disorders. Particularly, the deletion of the 16p11.2 locus is associated with autism spectrum disorder, intellectual disability, and several other features. Earlier studies highlighted the implication of Kctd13 genetic imbalance in 16p11.2 deletion th...
Chang, Jinfeng Ciais, Philippe Gasser, Thomas Smith, Pete Herrero, Mario Havlík, Petr Obersteiner, Michael Guenet, Bertrand Goll, Daniel S. Li, Wei
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Published in
Nature Communications
Grasslands, and the livestock that live there, are dynamic sources and sinks of greenhouse gases, but what controls these fluxes remains poorly characterized. Here the authors show that on the global level, grasslands are climate neutral owing to the cancelling effects of managed vs. natural systems.
Montigny, Audrey Tavormina, Patrizia Duboe, Carine San Clémente, Hélène Aguilar, Marielle Valenti, Philippe Lauressergues, Dominique Combier, Jean-Philippe Plaza, Serge
Published in
Genome Biology
BackgroundRecent genome-wide studies of many species reveal the existence of a myriad of RNAs differing in size, coding potential and function. Among these are the long non-coding RNAs, some of them producing functional small peptides via the translation of short ORFs. It now appears that any kind of RNA presumably has a potential to encode small p...
Gaete, Stanie Auguste, Aviane Bhakkan, Bernard Peruvien, Jessica Herrmann-Storck, Cecile Socrier, Youri Diedhiou, Abdoulaye Deloumeaux, Jacqueline
Published in
BMC Cancer
BackgroundCervical cancer is the fourth cancer worldwide. The Human Papilloma Virus is responsible for 99% of the cases but the distribution of its genotypes varies among populations. We aimed to identify HPV genotypes distribution in women with grade 2/3 cervical intraepithelial dysplasia or invasive cervical cancer in Guadeloupe, a French Caribbe...
Jenkins, Alex. S. Alvarez, Lara San Emeterio Memshawy, Samh Bortolotti, Paolo Cros, Vincent Freitas, Paulo P. Ferreira, Ricardo
Published in
Communications Physics
The control and manipulation of spin waves holds promise for miniaturized radio-frequency spintronic devices. The authors demonstrate electrical access to the dynamics of magnetic vortices in confined geometries: a new avenue of research for future applications exploiting super high frequency behaviour for microwave communications and computing app...
Droillard, Clément Lemaitre, Evelyne Amelot, Michel Blanchard, Yannick Keita, Alassane Eterradossi, Nicolas Le Gall-Reculé, Ghislaine
Published in
BMC Veterinary Research
BackgroundRabbit haemorrhagic disease virus Lagovirus europaeus/GI.1d variant (GI.1d/RHDV) was identified in 1990 in France, and until the emergence of the new genotype GI.2, it was the main variant circulating in the country. The early stages of RHDV infection have been described in a few studies of rabbits experimentally infected with earlier str...
Yoo, Myoung-Woo Tornos, J. Sander, A. Lin, Ling-Fang Mohanta, Narayan Peralta, A. Sanchez-Manzano, D. Gallego, F. Haskel, D. Freeland, J. W.
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Published in
Nature Communications
The anomalous Hall effect (AHE) occurs in ferromagnets caused by intrinsic and extrinsic mechanisms. Here, Yoo et al. report large anomalous Hall conductivity and Hall angle at the interface between a ferromagnet La0.7Sr0.3MnO3 and a semimetallic SrIrO3, due to the interplay between correlated physics and topological phenomena.
Challenger, Joseph D. Olivera Mesa, Daniela Da, Dari F. Yerbanga, R. Serge Lefèvre, Thierry Cohuet, Anna Churcher, Thomas S.
Published in
Nature Communications
Malaria transmission-blocking vaccines are in development, but roll-out strategies have not been assessed. Here, the authors show that transmission-blocking activity is likely to be higher in the field than in laboratory conditions, and that school-aged children are an important group to target.
