Lachaux, Marlène Thomas, Emilie Bogdanove, Adam J. Szurek, Boris Hutin, Mathilde
Published in
Rice
BackgroundXanthomonas oryzae pv. oryzae (Xoo) causes bacterial leaf blight, a devastating disease of rice. Among the type-3 effectors secreted by Xoo to support pathogen virulence, the Transcription Activator-Like Effector (TALE) family plays a critical role. Some TALEs are major virulence factors that activate susceptibility (S) genes, overexpress...
Fischman, Sébastien Pérez-Anker, Javiera Tognetti, Linda Di Naro, Angelo Suppa, Mariano Cinotti, Elisa Viel, Théo Monnier, Jilliana Rubegni, Pietro del Marmol, Véronique
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Published in
Scientific Reports
Diagnosis based on histopathology for skin cancer detection is today’s gold standard and relies on the presence or absence of biomarkers and cellular atypia. However it suffers drawbacks: it requires a strong expertise and is time-consuming. Moreover the notion of atypia or dysplasia of the visible cells used for diagnosis is very subjective, with ...
Parrot, Michel Němec, Frantisěk Cohen, Morris B. Gołkowski, Mark
Published in
Earth, Planets and Space
A spectrogram of Power Line Harmonic Radiation (PLHR) consists of a set of lines with frequency spacing corresponding exactly to 50 or 60 Hz. It is distinct from a spectrogram of Magnetospheric Line Radiation (MLR) where the lines are not equidistant and drift in frequency. PLHR and MLR propagate in the ionosphere and the magnetosphere and are reco...
Maitre, Apolline Wu-Chuang, Alejandra Aželytė, Justė Palinauskas, Vaidas Mateos-Hernández, Lourdes Obregon, Dasiel Hodžić, Adnan Valiente Moro, Claire Estrada-Peña, Agustín Paoli, Jean-Christophe
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Published in
Parasites & Vectors
Human and animal pathogens that are transmitted by arthropods are a global concern, particularly those vectored by ticks (e.g. Borrelia burgdorferi and tick-borne encephalitis virus) and mosquitoes (e.g. malaria and dengue virus). Breaking the circulation of pathogens in permanent foci by controlling vectors using acaricide-based approaches is thre...
Pronier, Elodie Imanci, Aygun Selimoglu-Buet, Dorothée Badaoui, Bouchra Itzykson, Raphael Roger, Thierry Jego, Chloé Naimo, Audrey Francillette, Maëla Breckler, Marie
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Published in
Communications Biology
To improve our understanding of the pathological role of TET2 mutations, Pronier, Imanci et al. use mice and human cells to show that TET2 downregulation promotes the production of macrophage migration inhibitory factor (MIF). In addition they show that whilst TET2 is recruited to the MIF promoter in healthy monocytes, decreased TET2 expression res...
Can, Hüseyin Aksoy Gökmen, Ayşegül Döşkaya, Mert Erkunt Alak, Sedef Değirmenci Döşkaya, Aysu Karakavuk, Muhammet Köseoğlu, Ahmet Efe Karakavuk, Tuğba Gül, Ceren Güvendi, Mervenur
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Published in
BMC Infectious Diseases
BackgroundDiscovery of new Toxoplasma gondii serotyping epitopes is important due to reports showing the influence of genotype on the severity of toxoplasmosis. In Turkey, genotypes belonging to type II, type III and Africa 1 lineages were mainly detected. The present study focused on to find out epitopes with high discriminative capacity to seroty...
Huynh, Ly Na Diarra, Adama Zan Nguyen, Hong Sang Tran, Long Bien Do, Van Nguyen Ly, Tran Duc Anh Ho, Van Hoang Nguyen, Xuan Quang Parola, Philippe
Published in
Parasites & Vectors
BackgroundMatrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is a tool that has revolutionised clinical microbiology and has recently been described as an innovative and effective approach to arthropod identification.MethodsIn this study, mosquitoes were captured in Vietnam using four different methods (huma...
Olga, Kolesnikova Amélie, Zachayus Simon, Pichard Judit, Osz Natacha, Rochel Paola, Rossolillo Isabelle, Kolb-Cheynel Nathalie, Troffer-Charlier Emmanuel, Compe Olivier, Bensaude
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Published in
Scientific Reports
The Baculovirus/insect cell expression system is a powerful technology for reconstitution of eukaryotic macromolecular assemblies. Most multigene expression platforms rely on Tn7-mediated transposition for transferring the expression cassette into the baculoviral genome. This allows a rigorous characterization of recombinant bacmids but involves mu...
de Miranda, Joachim R. Brettell, Laura E. Chejanovsky, Nor Childers, Anna K. Dalmon, Anne Deboutte, Ward de Graaf, Dirk C. Doublet, Vincent Gebremedhn, Haftom Genersch, Elke
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Published in
Virology Journal
In 1977, a sample of diseased adult honeybees (Apis mellifera) from Egypt was found to contain large amounts of a previously unknown virus, Egypt bee virus, which was subsequently shown to be serologically related to deformed wing virus (DWV). By sequencing the original isolate, we demonstrate that Egypt bee virus is in fact a fourth unique, major ...
Rypens, Charlotte Bertucci, François Finetti, Pascal Robertson, Fredika Fernandez, Sandra V. Ueno, Naoto Woodward, Wendy A. Van Golen, Kenneth Vermeulen, Peter Dirix, Luc
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Published in
npj Breast Cancer
Inflammatory breast cancer (IBC) is an aggressive disease for which the spectrum of preclinical models was rather limited in the past. More recently, novel cell lines and xenografts have been developed. This study evaluates the transcriptome of an extended series of IBC preclinical models and performed a comparative analysis with patient samples to...