Hura, Angelia J. Hawley, Hannah R. Tan, Wei Jun Penny, Rebecca J. Jacobsen, Jessie C. Fitzsimons, Helen L.
Published in
Molecular Brain
Coenzyme Q8A encodes the homologue of yeast coq8, an ATPase that is required for the biosynthesis of Coenzyme Q10, an essential component of the electron transport chain. Mutations in COQ8A in humans result in CoQ10 deficiency, the clinical features of which include early-onset cerebellar ataxia, seizures and intellectual disability. The rapid adva...
Arrieta, Oscar Molina-Romero, Camilo Cornejo-Granados, Fernanda Marquina-Castillo, Brenda Avilés-Salas, Alejandro López-Leal, Gamaliel Cardona, Andrés F. Ortega-Gómez, Alette Orozco-Morales, Mario Ochoa-Leyva, Adrián
...
Published in
Scientific Reports
Lung cancer (LC) and pulmonary tuberculosis (TB) are the deadliest neoplastic and bacterial infectious diseases worldwide, respectively. Clinicians and pathologists have long discussed the co-existence of LC and TB, and several epidemiologic studies have presented evidence indicating that TB could be associated with the development of LC, particula...
Wang, Shixia Yates, Nicole L. Pollara, Justin Voronin, Yegor Stanfield-Oakley, Sherry Han, Dong Hu, Guangnan Li, Wei Ferrari, Guido Tomaras, Georgia D.
...
Published in
npj Vaccines
Since publishing our original reports on the safety and immunogenicity of a polyvalent DNA prime-protein boost HIV vaccine (PDPHV) which elicited high titer antibody responses with broad specificity, neutralizing activities to multiple HIV-1 subtypes, as well as poly-functional T cell responses, accumulated findings from other HIV vaccine studies i...
Duque, Marc Lee-Kubli, Corinne A. Tufail, Yusuf Magaram, Uri Patel, Janki Chakraborty, Ahana Mendoza Lopez, Jose Edsinger, Eric Vasan, Aditya Shiao, Rani
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Published in
Nature Communications
Ultrasound can be used to non-invasively control neuronal functions. Here the authors report the use of human Transient receptor potential ankyrin 1 (hsTRPA1) to achieve ultrasound sensitivity in mammalian cells, and show that it can be used to manipulate neurons in the mammalian brain.
Xia, Tian Kumar, Ashnil Fulham, Michael Feng, Dagan Wang, Yue Kim, Eun Young Jung, Younhyun Kim, Jinman
Published in
Scientific Reports
Radiogenomics relationships (RRs) aims to identify statistically significant correlations between medical image features and molecular characteristics from analysing tissue samples. Previous radiogenomics studies mainly relied on a single category of image feature extraction techniques (ETs); these are (i) handcrafted ETs that encompass visual imag...
Bairova, T. A. Nemchinova, N. V. Belyaeva, E. V. Sambyalova, A. Yu. Ershova, O. A. Rychkova, L. V.
Published in
Russian Journal of Genetics
AbstractWe compared the frequencies of genotypes and alleles of the C3435T and C1236T polymorphisms of the multidrug resistance gene (ABCB1) among adolescents of the indigenous populations of North Asia: Tofalars, Evenks, Soyots. The sample included 86 people (Tofalars—26 people, Evenks—38, Soyots—22). The average age was 14 [12.5–15.5] years for S...
Seadawy, Aly R. Younis, Muhammad Althobaiti, Ali
Published in
Optical and Quantum Electronics
In this manuscript, various types of breather, periodic cross-kink and rational solitons, M-shaped rational solutions with one and two kink and multi-waves will be discussed for Bose–Einstien condensate (BEC) model. We will compute the Kuznetsov–Ma breather, Akhmediev breather and generalized breather along with discussion on the interaction betwee...
Manubolu, Venkat S. Roy, Sion K. Budoff, Matthew J.
Published in
Current Cardiovascular Imaging Reports
Purpose of reviewTo provide an update and to outline the status of coronary computer tomography angiography (CCTA) in the evaluation of coronary plaques and discuss the relevance of serial CCTA in guiding cardiovascular risk stratification and anti-atherosclerotic medical therapy.Recent findingsCoronary CTA is now the imaging modality of choice in ...
Janoszka, Katarzyna Czaplicka, Marianna
Published in
Water, Air, & Soil Pollution
The major biomass burning tracers are thermal degradation products from the biopolymer cellulose, namely the didehydromonosaccharide derivatives levoglucosan, galactosan, and mannosan and the resin acid derivative dehydroabietic acid, with a minor contribution from β-sitosterol. Levoglucosan, galactosan, and mannosan were measured at two sites in S...
Wurman, Peter R. Barrett, Samuel Kawamoto, Kenta MacGlashan, James Subramanian, Kaushik Walsh, Thomas J. Capobianco, Roberto Devlic, Alisa Eckert, Franziska Fuchs, Florian
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Published in
Nature
Using the game Gran Turismo, an agent was trained with a combination of deep reinforcement learning algorithms and specialized training scenarios, demonstrating success against championship-level human racers.
