Koutroumpakis, Efstratios Palaskas, Nicolas L. Lin, Steven H. Abe, Jun-ichi Liao, Zhongxing Banchs, Jose Deswal, Anita Yusuf, Syed Wamique
Published in
Chemotherapy
Despite the advancements of modern radiotherapy, radiation-induced heart disease remains a common cause of morbidity and mortality amongst cancer survivors. This review outlines the basic mechanism, clinical presentation, risk stratification, early detection, possible mitigation, and treatment of this condition.
Hong, Chuen Lin Broadbent, Jonathan Mark Thomson, William Murray
Published in
Caries Research
There has been considerable research focussed on the occurrence and aetiology of developmental defects of enamel, but less is known about the extent to which enamel-defect-affected teeth may be at greater risk for dental caries. The Dunedin Multidisciplinary Health and Development Study is a prospective cohort study of 1,037 children born in Dunedi...
Rubio-Aliaga, Isabel
Published in
Kidney and Blood Pressure Research
Background: The aging population is increasing rapidly, much faster than our understanding on how to promote healthy aging free of multimorbidities. The aging kidney shows a decline in its function. Whether this decline is preventable or physiological is still debated. Main risks factors for developing CKD are aging common comorbidites, such as hyp...
Ahmad, Naveed Khan, Tariq Jamal, Syed Muhammad
Published in
Intervirology
Background: Dengue fever is one of the most common human arbovirus infections worldwide. In Pakistan, dengue initially became endemic in the big cities and then expanded to remote areas of the country. The current study reports the dengue epidemics, anti-DENV antibodies prevalence during the active and post-dengue infection, risk factors, disease s...
Richerson, Wesley T. Umfleet, Laura G. Schmit, Brian D. Wolfgram, Dawn F.
Published in
Nephron
Introduction: Patients on hemodialysis (HD) have a significant burden of cognitive impairment. Characterizing the cerebral structural changes in HD patients compared to healthy controls and evaluating the relationship of cerebral structural integrity with cognitive performance in HD patients can help clarify the pathophysiology of the cognitive imp...
Dieckmann, Klaus-Peter Hennig, Finja Anheuser, Petra Gehrckens, Ralf Viehweger, Florian Wülfing, Christian Belge, Gazanfer
Published in
Urologia Internationalis
Background: MicroRNA-371a-3p (miR-371), the novel serum biomarker of testicular germ cell tumours (GCTs), is produced by undifferentiated subtypes of GCTs but not by teratoma. Cystic teratoma developing from retroperitoneal metastases of GCT subsequent to chemotherapy had been shown to contain high levels of classical serum tumour markers of GCT in...
Shukla, Aditi Orozco, Tatiana
Published in
Obesity Facts
Khaddour, Karam Harrison, Nigel Govindan, Ashwin Campian, Jian L.
Published in
Case Reports in Oncology
Temozolomide (TMZ) is an oral alkylating agent that is considered the standard therapy in primary intracranial malignancies. The medication is well tolerated with a most common side effect of bone marrow suppression that is encountered in a small proportion of patients, often reversible with medication discontinuation and supportive treatment. Rare...
Demartini Jr., Zeferino Teixeira, Bernardo Corrêa de Almeida Koppe, Gelson Luiz Gatto, Luana A.M.
Published in
Pediatric Neurosurgery
Grgić, Dora Čuković Čavka, Silvija Elveđi Gašparović, Vesna Turk, Nikša Brinar, Marko Marušić, Zlatko Krznarić, Željko
Published in
Case Reports in Gastroenterology
Inflammatory bowel diseases (IBD) usually affect women in their fertile years and, therefore, have implications for their fertility and pregnancy. The presence of IBD during pregnancy has been shown to adversely affect pregnancy outcomes, and increased rates of preterm delivery and of spontaneous abortion have been reported. An onset of acute sever...