Published in Nephron
Introduction: Apolipoprotein L1 (APOL1) plays an important role in cholesterol metabolism and attenuation of low-density lipoprotein (LDL) oxidation. While protecting against Trypanosoma brucei rhodesiense infection, APOL1 risk alleles confer greater risk for CKD and cardiovascular disease among patients of African descent. Objectives: We investiga...
Published in Verhaltenstherapie
Die Psychotherapiereform verändert die Ausbildung von Psychotherapeutinnen und -therapeuten in Deutschland: Zukünftig sollen klinisch-psychologische Masterstudiengänge mit einer staatlichen Approbationsprüfung in Psychotherapie abgeschlossen werden. Die hochschulische Lehre muss entsprechend psychotherapeutische Basisfertigkeiten praktisch vermitte...
Published in Journal of Vascular Research
Introduction: The exocytosis of cyclophilin A (CyPA) by a vesicular pathway in response to reactive oxygen species has been determined. However, other sources of extracellular CyPA remain obscure. Objective: The aim of this study was to determine the role of autophagy in the secretion of CyPA. Methods and Results: Rapamycin induced the activation o...
Published in Case Reports in Neurology
COVID-19 has been associated with a hypercoagulable state causing cardiovascular and neurovascular complications. To further characterize cerebrovascular disease (CVD) in COVID-19, we review the current literature of published cases and additionally report the clinical presentation, laboratory and diagnostic testing results of 12 cases with COVID-1...
Published in Case Reports in Oncology
Soft tissue sarcomas are common neoplasms accounting for 1% of all adult malignancies; however, soft tissue sarcomas infrequently arise from the abdominal viscera. Many case reports discuss gastric and esophageal neoplasms. In the group of gastrointestinal liposarcomas, primary duodenal liposarcomas are among the rarest, with only three previous ca...
Published in Dementia and Geriatric Cognitive Disorders
Introduction: The disabling effects of dementia, an incurable disease with little effect on mortality, affect society far more than many other conditions. Objective: The aim of this study was to stop or delay the onset of dementia using low-cost methods such as physical exercise. Methods: Senescence-accelerated model-prone (SAMP) 10 mice were made ...
Published in Oncology
Background: In patients with colorectal cancer, the rate of recurrence increases as the histologic stage progresses. However, the prediction of recurrence in individual patients is difficult. Many studies have reported on the relation between outcomes and tissue-infiltrating lymphocytes (TILs). The aim of our study was to clarify the relation betwe...
Published in Skin Appendage Disorders
Introduction: Nail involvement in psoriasis occurs in up to 30–50% of patients, and 5–10% may have isolated nail disease. Onychoscopy, a noninvasive tool, might obviate the need for nail biopsy, which is a diagnostic gold standard. Objective: The aim of this study was to evaluate onychoscopic features of nail unit in patients with nail psoriasis. M...
Published in Nephron
In our opinion, the use of heparin could play a crucial role in these patients. In fact, recent studies have shown that heparin, the most commonly used anticoagulant during HD procedures, had anti-inflammatory properties and a direct antiviral action, due to its ability to prevent SARS-CoV-2 pseudovirus entry into host cells. These activities, toge...
Published in Cerebrovascular Diseases
Background: Genetic variants may play a role in determining the location of cerebral atherosclerosis. We aimed to investigate the association between RNF213, MMP2, and genetic polymorphisms linked to vascular tortuosity with the location of cerebral arterial atherosclerosis. Methods: A prospective case-control study was conducted on patients with i...
