Whole genome sequencing (WGS) enables complete characterization of bacterial pathogenic isolates at single nucleotide resolution, making it the ultimate tool for routine surveillance and outbreak investigation. The lack of standardization, and the variation regarding bioinformatics workflows and parameters, however, complicates interoperability amo...
Published in Molecular Autism
BackgroundPrevious studies have reported a negative psychological and mental health impact of the COVID-19 pandemic. This impact is likely to be stronger for people with autism as they are at heightened risk of mental health problems and because the pandemic directly affects social functioning and everyday routines. We therefore examined COVID-19 p...
Published in BMJ Open Sport — Exercise Medicine
Objectives Recreational runners show a large interindividual variation in spatiotemporal characteristics. This research focused on slow runners and intended: (1) to document the variance in duty factor (DF) between runners in a real-life running setting and (2) examine whether the interindividual variation in DF and stride frequency (SF) relates to...
Published in Frontiers in Psychology
Several versions of the dot probe detection task are frequently used to assess maladaptive attentional processes associated with a broad range of psychopathology and health behavior, including eating behavior and weight. However, there are serious concerns about the reliability of the indices derived from the paradigm as measurement of attentional ...
Published in EURASIP Journal on Audio, Speech, and Music Processing
Localization of multiple speakers using microphone arrays remains a challenging problem, especially in the presence of noise and reverberation. State-of-the-art localization algorithms generally exploit the sparsity of speech in some representation for this purpose. Whereas the broadband approaches exploit time-domain sparsity for multi-speaker loc...
The classification of soft tissue tumors has evolved considerably in the last decade, largely due to advances in understanding the pathogenetic basis of many of these, sometimes rare, tumors. Deletion of Retinoblastoma 1 (RB1), a well-known tumor suppressor gene, has been implicated in the tumorigenesis of a particular group of soft tissue neoplasm...
Published in Life Science Alliance
The migrational propensity of neuroblastoma is affected by cell identity, but the mechanisms behind the divergence remain unknown. Using RNAi and time-lapse imaging, we show that ADRN-type NB cells exhibit RAC1- and kalirin-dependent nucleokinetic (NUC) migration that relies on several integral components of neuronal migration. Inhibition of NUC mi...
Published in npj Climate and Atmospheric Science
The land surface influences the atmospheric boundary layer (ABL) through its impacts on the partitioning of available energy into evaporation and warming. Previous research on understanding this complex link focused mainly on site-scale flux observations, gridded satellite observations, climate modeling, and machine-learning experiments. Observatio...
Published in Molecular Cancer
mRNA therapeutics have become the focus of molecular medicine research. Various mRNA applications have reached major milestones at high speed in the immuno-oncology field. This can be attributed to the knowledge that mRNA is one of nature’s core building blocks carrying important information and can be considered as a powerful vector for delivery o...
The through-thickness compressive behavior of fabric reinforcements is crucial in liquid composite molding manufacturing processes. Predictive simulations of the compressive response are thus necessary to enable a virtual processing workflow. These are complex however, as the compressive behavior of the reinforcement fabrics is non-linear. Altough ...
