State of the art of measurement uncertainty of serum ferritin
Published in Clinical Chemistry and Laboratory Medicine (CCLM)
Sodium and risk assessment of osmotic demyelination syndrome: the method matters!
Published in Clinical Chemistry and Laboratory Medicine (CCLM)
Use of thyroid function tests in urine: a position statement of the Belgian Thyroid Club
...Published in Clinical Chemistry and Laboratory Medicine (CCLM)
A sensitive LC-MS/MS methotrexate assay capable of assessing adherence to methotrexate therapy in rheumatoid arthritis
Published in Clinical Chemistry and Laboratory Medicine (CCLM)
Objectives To develop a sensitive liquid chromatography-tandem mass spectrometry method capable of measuring serum methotrexate in patients with rheumatoid arthritis to assess adherence to drug treatment. Methods Isotopically labelled internal standard and deionised water were added to sample prior to solid phase extraction using a Waters Oasis Max...
Determination of cortisone and cortisol in human scalp hair using an improved LC-MS/MS-based method
Published in Clinical Chemistry and Laboratory Medicine (CCLM)
Objectives Human scalp hair is an easily available but complex matrix for determination of cortisone and cortisol, and has been shown to reflect long-term glucocorticoid exposure. Hair glucocorticoid analysis has been used to detect hypo- and hypercortisolism. In this study, we describe the development and validation of a LC-MS/MS method for quanti...
The effect of hormonal contraceptive therapy on clinical laboratory parameters: a literature review
Published in Clinical Chemistry and Laboratory Medicine (CCLM)
Hormonal contraceptives (HC) are widely used among women in reproductive ages. In this review, the effects of HCs on 91 routine chemistry tests, metabolic tests, and tests for liver function, hemostatic system, renal function, hormones, vitamins and minerals were evaluated. Test parameters were differently affected by the dosage, duration, composit...
Reverse cascade testing from newborn screening: the opportunity to improve family healthcare outcomes
Published in Clinical Chemistry and Laboratory Medicine (CCLM)
Stability of fecal calprotectin extracts using the Diasorin® kit
Published in Clinical Chemistry and Laboratory Medicine (CCLM)
Measuring Intelligence and Growth Rate: Variations on Hibbard’s Intelligence Measure
Published in Journal of Artificial General Intelligence
In 2011, Hibbard suggested an intelligence measure for agents who compete in an adversarial sequence prediction game. We argue that Hibbard’s idea should actually be considered as two separate ideas: first, that the intelligence of such agents can be measured based on the growth rates of the runtimes of the competitors that they defeat; and second,...
Modeling the compliance of the human eye with elastic membranes based on a bionic approach
Published in Biomedical Engineering / Biomedizinische Technik
Objectives Together with the corneoscleral shell the intraocular pressure maintains the shape of the human eyeball and thus ensures both mechanical and optical integrity, whereby the relationship between the intraocular volume and pressure is described by the so-called ocular compliance. The compliance of the human eye is of significance in situati...
