Audi, Adawiah Sulaiman Shah Khairiyah, Sidek Syafirin, Ab Sani Najihah, Abu Bakar Ardif, Damiri Rizma, Mohd Zaid Marniza, Saad Adlinda, Alip
Published in
Advances in Modern Oncology Research
Background: Pazopanib is a vascular endothelial growth factor (VEGF) tyrosine kinase inhibitor (TKI) that was approved as first line treatment for advanced renal cell carcinoma (aRCC). The pivotal trial showed significant increase in median progression free survival (mPFS) of 9.2 months versus 4.0 months with placebo and objective response rate of ...
Abdul, Wahid Anwer Mariam, Salim Fahd, Shah Taqi, Pirzada Irfan, ul Islam Nasir Amina, Khan
Published in
Advances in Modern Oncology Research
Background: Staging the axilla via Sentinel Node biopsy (SLNBx) is a standard technique for clinically and radiologically negative patients. The timing to do the SLNBx before or after Neo Adj Chemo (NAC) is controversial. The aim of the study is to see the outcomes of SLNBX in our patients who underwent NAC in clinically and radiological negative a...
Dario, Didona Biagio, Didona Antonio, G Richetta Carmen, Cantisani Elisa, Moliterni Stefano, Calvieri Giovanni, Paolino
Published in
Advances in Modern Oncology Research
Paraneoplastic pemphigus is a rare autoimmune disease of the skin associated with neoplasm. Nowadays, the pathogenesis of paraneoplastic pemphigus is not fully understood. Due to its rarity, various criteria have been proposed for the diagnosis. For this reason, several diagnostic methods have been considered useful for the diagnosis of paraneoplas...
Omar, Al Ustwani Neha, Gupta Adrienne, Groman Hongbin, Chen
Published in
Advances in Modern Oncology Research
The management of advanced malignancies in solid organ transplant (SOT) recipients is not well-structured as the patients need immunosuppressive agents to avoid graft rejection. Simultaneous administration of chemotherapy and immunosuppressive agents may increase treatment toxicities. The data of SOT recipients treated at Roswell Park Cancer Instit...
Joanna, Lim S, . Y . Lau N, . S . Ahmad Bashah K, . N . Lai W, . X . Wen D, . J . Park B, . J . Pope T, . Nguyen - Dumont M, . C . Southey L, . K . Wah
...
Published in
Advances in Modern Oncology Research
Background: Germline BRCA1 or BRCA2 pathogenic variants in ovarian cancer patients may be predictive of sensitivity to platinum derivatives and PARP enzyme inhibitors. Population studies have indicated a >10% prevalence of BRCA1/2 pathogenic variants with wide variance amongst ethnically different populations. We aim to establish the first populati...
Dai, Wee Lee Fuad, Ismail
Published in
Advances in Modern Oncology Research
Background: Basal cell carcinoma (BCC) is relatively uncommon in Malaysia with non-melanomatous skin cancer being the 12th most common malignancy in Malaysia.Metastatic basal cell carcinoma (MBCC) is extremely rare and the incidence is estimated to be 0.0028% to 0.55% among all BCC. We report a case of MBCC with a summary of clinical and histopatho...
Ying, Ying Sum Usaantini, Amriteshwari Devi Junie, Yu - Yen Khoo
Published in
Advances in Modern Oncology Research
Background: Head and neck soft tissue sarcomas are rare and leiomyosarcoma accounts for only 4%[1]. There have only been 50 cases of glottic leiomyosarcomas reported in scientific literature to date. Immunohistochemistry is pivotal in establishing diagnosis. Surgery remains mainstay of treatment for glottic leiomyosarcomas. We report a case of glot...
Ahmad, Naufal Md Alwi Flora, Li Tze Chong Sucharit, Pongprakyun Moharzudi, Mohamed
Published in
Advances in Modern Oncology Research
Background: Urachal cancers arising from the urachus or its remnants, is a very rare and aggressive type of cancer in which occurrence is only about 0.01% of all adult cancers. Till date, there is no standard chemotherapy regimes or randomized trials due to the rarity of the disease. In 2007, not more than 350 written case reports in English has be...
Zhi, Hao Liew Soe, Khine Myat
Published in
Advances in Modern Oncology Research
Background: The gastrointestinal stromal tumors (GISTs) account for less than 1% of all malignancies, but they are usually originate from the wall of the GI tract. Primary extra-gastrointestinal GISTs are rarer. Case: A 74 year-old Chinese gentleman presented with obstructive urinary symptoms in early 2012. TURP was done and histopathology result r...
Sweta, Sharma Tej, Prakash Soni Nidhi, Patni
Published in
Advances in Modern Oncology Research
This study aims to determine the outcomes and patterns of failure in gingivo-buccal oral squamous cell carcinoma (OSCC) after postoperative intensity modulated radiotherapy (IMRT) with concurrent chemotherapy. A prospective single-arm study was conducted at our institute from October 2014 to June 2016. Fourty-two patients with postoperative gingivo...
