Wu, Lingling Fang, Changping Zhang, Jun Ye, Yanchou Zhao, Haiyan
Published in
Gynecologic and Obstetric Investigation
Objectives: Insulin receptor substrate 1 (IRS1) is a crucial factor in the insulin signaling pathway. IRS1 gene polymorphism rs1801278 in mothers has been reported to be associated with gestational diabetes mellitus (GDM). However, it is not clear whether IRS1 gene polymorphism rs1801278 in fetuses is associated with their mothers’ GDM morbidity. T...
Cheng, Li-Rong Lilly
Published in
Folia Phoniatrica et Logopaedica
Baran, Julia A. Tsai, Steven D. Isaza, Amber Brodeur, Garrett M. MacFarland, Suzanne P. Zelley, Kristin Adams, Denise M. Franco, Aime T. Bauer, Andrew J.
Published in
Hormone Research in Paediatrics
Introduction: Phosphatase and tensin homolog (PTEN) hamartoma tumor syndrome (PHTS) comprises a collection of clinical features characterized by constitutional variants in PTEN. Several guidelines recommend thyroid screening, beginning at the pediatric age at the time of PHTS diagnosis; however, the benefits of early surveillance has not been well ...
Egesten, Arne Herwald, Heiko
Published in
Journal of Innate Immunity
Izmailova, Elena S. Wood, William A. Liu, Qi Zipunnikov, Vadim Bloomfield, Daniel Homsy, Jason Hoffmann, Steven C. Wagner, John A. Menetski, Joseph P.
Published in
Digital Biomarkers
Clinical safety findings remain one of the reasons for attrition of drug candidates during clinical development. Cardiovascular liabilities are not consistently detected in early-stage clinical trials and often become apparent when drugs are administered chronically for extended periods of time. Vital sign data collection outside of the clinic offe...
Cintra, Rafael Guerra Wajnsztejn, Rubens Trevisan, Camila Martins Zaia, Victor Laganà, Antonio Simone Bianco, Bianca Montagna, Erik
Published in
Hormone Research in Paediatrics
Background/Aims: Kisspeptin (KP) is a key player in the regulation of the release of gonadotropin-releasing hormone (GnRH), which increases the secretion of gonadotropin during puberty to establish reproductive function and regulate the hypothalamic-pituitary-gonadal axis. Premature activation of GnRH secretion leads to idiopathic/central gonadotro...
Trifonov, Vladimir A. Cioffi, Marcelo B. Liehr, Thomas
Published in
Cytogenetic and Genome Research
Pampanini, Valentina Hassan, Jasmin Oliver, Elizabeth Stukenborg, Jan-Bernd Damdimopoulou, Pauliina Jahnukainen, Kirsi
Published in
Hormone Research in Paediatrics
The increasing cure rate of cancer has led to a vast population of survivors having to face the late adverse effects of oncological treatments, with fertility impairment being one of the most sensitive issues for patients. Different options to preserve the fertility of adult patients are routinely used in clinical practice. However, fertility prese...
da Silva, David S. da Silva Filho, Heriberto F. Cioffi, Marcelo B. de Oliveira, Edivaldo H.C. Gomes, Anderson J.B.
Published in
Cytogenetic and Genome Research
With 82 species currently described, the genus Leptodactylus is the most diverse and representative one in the family Leptodactylidae. Concerning chromosomal organization, this genus represents an interesting and underexplored group since data from molecular cytogenetics are incipient, and little is known about the organization and distribution of ...
Travaglino, Antonio Raffone, Antonio Gencarelli, Annarita Saracinelli, Serena Zullo, Fulvio Insabato, Luigi
Published in
Pathobiology
Here, we present a case that highlights the crucial pitfalls related to the presence of morular metaplasia (MM) in endometrioid carcinoma, which are insufficiently recognized in the routine pathology practice. A 45-year-old woman underwent hysterectomy with rectosigmoidectomy due to a 11-cm mass involving uterus, right ovary, and rectosigmoid colon...
