Aronna, M S Guglielmi, R Moschen, L M
Published in
Infectious Disease Modelling
In this work we fit an epidemiological model SEIAQR (Susceptible - Exposed - Infectious - Asymptomatic - Quarantined - Removed) to the data of the first COVID-19 outbreak in Rio de Janeiro, Brazil. Particular emphasis is given to the unreported rate, that is, the proportion of infected individuals that is not detected by the health system. The eval...
Chen, Rong Hu, Tianyuan Wang, Ming Hu, Yuhan Chen, Shu Wei, Qiuhui Yin, Xiaopu Xie, Tian
Published in
Synthetic and systems biotechnology
Leaf and tuber extracts of Curcuma wenyujin contain a mixture of curcuminoids. However, the curcuminoid constituents and their molecular mechanisms are poorly understood, and the relevant curcumin synthases remain unclear. In this study, we comprehensively compared the metabolite profiles of the leaf and tuber tissues of C. wenyujin. A total of 11 ...
Xu, Yue You, Yuan Yi, Luyao Wu, Xiaoyi Zhao, Yaning Yu, Jian Liu, He Shen, Ya Guo, Jingmei Huang, Cui
...
Published in
Bioactive Materials
• Nanomaterials can adhere to tooth and target acidic biofilms specifically. • Application of caries prevention and tooth defect restoration. • Guidance for the innovation of the existing post-defect restoration strategies. • The multidrug delivery system exerts antibacterial and restorative abilities on demand. • Bacteria-responsive system resists...
Wang, Jinping Qu, Chang Shao, Xinyue Song, Guoqiang Sun, Jingyu Shi, Donghong Jia, Ran An, Hailong Wang, Hongjun
Published in
Bioactive Materials
• Demonstrate the efficacy of multifunctional nanoparticles in degrading mutant p53 while activating wide-type p53. • Develop “carrier-free nanoprodrug” for pH-induced delivery of dual ions (Zn2+, Mn2+) and H2O2 with reduced side effects. • Readily extend the simple, green, yet efficient synthesis route to other ion-doped metal peroxide nanoparticl...
Lee, Min Suk Jeon, Jin Park, Sihyeon Lim, Juhan Yang, Hee Seok
Published in
Bioactive Materials
• Bioactive peptide-containing scaffold was fabricated via simple freeze-thaw cycles, and subsequently, the surface was modified with adhesive protein. • We confirmed that the multifunctional biopeptides regulated the migration of macrophages and enhanced osteogenic differentiation. • The bioactive peptide-containing scaffold showed much faster and...
Park, Jae Hee Jo, Seung Bin Lee, Jung-Hwan Lee, Hae-Hyoung Knowles, Jonathan C. Kim, Hae-Won
Published in
Bioactive Materials
• Discuss the cutting-edge findings on the role of matrix rigidity in dictating diverse cell behaviors. • Underscore the dynamic matrix rigidity that interplays with cells, and the related pathophysiological phenomena. • Illuminate the significance of matrix rigidity in clinically-relevant settings.
Zhao, Puxiang Feng, Yue Zhou, Youquan Tan, Cuiying Liu, Mingxian
Published in
Bioactive Materials
• Au particles with diameter of 5–10 nm are filled into the lumen of halloysite. • [email protected] enhanced the mechanical and anti-bacterial properties of chitin. • [email protected] hydrogels exhibit photothermal effect with good compatibility. • Hydrogel dressing shows hemostasis and promoting wound healing performance.
Zhang, Linghong Li, Tao Yu, Yan Shi, Kun Bei, Zhongwu Qian, Yongjun Qian, Zhiyong
Published in
Bioactive Materials
• An injectable self-healing conductive hydrogel was synthesized for the treatment of myocardial infarction (MI). • The OGGP3 hydrogel had elastic modulus (20.77 kPa) and conductivity (5.52 × 10−4 S/cm) that matched the natural heart. • The hydrogel could protect cardiac function, reduce arrhythmia susceptibility and the resistivity of cardiac scar...
Lv, Ziyan Ma, Wenjie Zhang, Ping Lu, Zhaoxin Zhou, Libang Meng, Fanqiang Wang, Zuwei Bie, Xiaomei
Published in
Synthetic and Systems Biotechnology
Bacillomycin D is a cyclic lipopeptide produced by Bacillus amyloliquefaciens fmbJ. At present, no relevant report has described the combinatorial biosynthesis of bacillomycin D. Due to the strong biosynthetic potential of the communication-mediating (COM) domains, its crosstalk between NRPS subunits has been studied to some extent, but the interac...
Fu, Ya-nan Li, Yongsan Deng, Bo Yu, Yingjie Liu, Fang Wang, Lei Chen, Guang Tao, Lei Wei, Yen Wang, Xing
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Published in
Bioactive Materials
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