Ward, Ryan D Winiger, Vanessa Kandel, Eric R Balsam, Peter D Simpson, Eleanor H
Published in
Frontiers in Aging Neuroscience
Orbitofrontal cortex (OFC) function is critical to decision making and behavior based on the value of expected outcomes. While some of the roles the OFC plays in value computations and behavior have been identified, the role of the OFC in modulating cognitive resources based on reward expectancy has not been explored. Here we assessed the involveme...
Clément Bailly Thomas Eugène Marie-Laure Couec Marion STRULLU Eric Frampas Loïc Campion Françoise Kraeber-Bodéré Caroline Bodet-Milin
Published in
Frontiers in Medicine
Objective: Burkitt lymphoma (BL) is a rare and aggressive form of B-cell lymphoma that is curable using intensive chemotherapy. Obtaining a complete response (CR) at the end of induction chemotherapy is a major prognostic factor. This study retrospectively evaluates the potential impact of 18FDG-PET in the management of children with BL after induc...
Demeure, Kevin Duriez Elodie Domon, Bruno Niclou, Simone P.
Published in
Frontiers in Genetics
The search for clinically useful protein biomarkers using advanced mass spectrometry approaches represents a major focus in cancer research. However, the direct analysis of human samples may be challenging due to limited availability, the absence of appropriate control samples, or the large background variability observed in patient material. As an...
Kevin Demeure Elodie Duriez Bruno Domon Simone P. Niclou
Published in
Frontiers in Genetics
Michael Schnekenburger Karius, Tommy Marc Diederich
Published in
Frontiers in Pharmacology
Glutathione S-transferases (GSTs) are phase II drug detoxifying enzymes that play an essential role in the maintenance of cell integrity and protection against DNA damage by catalyzing the conjugation of glutathione to a wide variety of exo- and endogenous electrophilic substrates. Glutathione S-transferase P1 (GSTP1), the gene encoding the pi-clas...
Published in
Frontiers in Behavioral Neuroscience
Published in
Frontiers in Behavioral Neuroscience
Chen, Chia-Chien Lu, Ju Yi Zuo
Published in
Frontiers in Neuroanatomy
Chen, Chia-Chien Lu, Ju Yi Zuo
Published in
Frontiers in Neuroanatomy
Wong, Tze Fang Takeda, Takashi Li, Bin Tsuiji, Kenji Kondo, Akiko Tadakawa, Mari Nagase, Satoru Yaegashi, Nobuo
Published in
International Journal of Clinical Oncology
BackgroundUterine leiomyosarcomas generally do not respond well to standard chemotherapy. We previously demonstrated that curcumin, the active ingredient derived from the herb Curcuma longa, inhibits uterine leiomyosarcoma cells in vitro via the inhibition of the AKT–mammalian target of rapamycin (mTOR) pathway. As a preclinical investigation, we p...
