Bakry, Ayyob M. Awad, Fathi S. Bobb, Julian A. El-Shall, M. Samy
Published in
ACS Omega
Heavy metal ions represent one of the most toxic and environmentally harmful pollutants of water sources. This work reports the development of a novel chelating nitrogen-doped carboxylated porous carbon (ND-CPC) adsorbent for the effective removal of the heavy metal ions Pb(II), Hg(II), and Cr(VI) from contaminated and polluted water sources. The N...
Kovaleva, Natalya A. Strelnikov, Ivan A. Zubova, Elena A.
Published in
ACS Omega
Some DNA sequences in crystals and in complexes with proteins can exist in the forms intermediate between the B- and A-DNA. Based on this, it was implied that the B-to-A transition for any DNA molecule should go through these intermediate forms also in kinetics. More precisely, the helix parameter Slide has to change first, and the molecule should ...
Lungu-Mitea, Sebastian Vogs, Carolina Carlsson, Gunnar Montag, Maximiliane Frieberg, Kim Oskarsson, Agneta Lundqvist, Johan
Published in
Environmental Science & Technology
Linking cellular toxicity to low-tier animal toxicity and beyond is crucial within the adverse outcome pathway concept and the 3R framework. This study aimed to determine and compare the bioavailable effect concentrations in zebrafish cell lines and embryos. Acute, short-term toxicity (48 h) of eight veterinary pharmaceuticals was measured in two z...
Sharpe, Ryan House, Robert A. Clarke, Matt J. Förstermann, Dominic Marie, John-Joseph Cibin, Giannantonio Zhou, Ke-Jin Playford, Helen Y. Bruce, Peter G. Islam, M. Saiful
...
Published in
Journal of the American Chemical Society
In the search for high energy density cathodes for next-generation lithium-ion batteries, the disordered rocksalt oxyfluorides are receiving significant attention due to their high capacity and lower voltage hysteresis compared with ordered Li-rich layered compounds. However, a deep understanding of these phenomena and their redox chemistry remains...
Dzijak, Rastislav Galeta, Juraj Vázquez, Arcadio Kozák, Jaroslav Matoušová, Marika Fulka, Helena Dračínský, Martin Vrabel, Milan
Published in
Jacs Au
The development of abiotic chemical reactions that can be performed in an organelle-specific manner can provide new opportunities in drug delivery and cell and chemical biology. However, due to the complexity of the cellular environment, this remains a significant challenge. Here, we introduce structurally redesigned bioorthogonal tetrazine reagent...
Yamada, Yuji
Published in
ACS Omega
Doxorubicin (DOX) is commonly used in chemotherapy and biomedical research because of its potent anticancer activity. Although DOX is water soluble, it precipitates when interacting with buffers, such as phosphate-buffered saline, or with drugs such as 5-fluorouracil (5-FU) and heparin. This study reports that DOX precipitates in neutral buffers an...
Majdecki, Maciej Grodek, Piotr Jurczak, Janusz
Published in
The Journal of Organic Chemistry
We report an enantioselective phase transfer α-chlorination of β-keto esters catalyzed by hybrid amide-based Cinchona derivatives. The chlorination process proceeds with proper quantitative yields (up to
Pálvölgyi, Ádám Márk Smith, Jakob Schnürch, Michael Bica-Schröder, Katharina
Published in
The Journal of Organic Chemistry
We report a straightforward and efficient Pd/enamine catalytic procedure for the direct asymmetric α-allylation of branched aldehydes. The use of simple chiral amines and easily prepared achiral or racemic phosphoric acids, together with a suitable Pd-source resulted in a highly active and enantioselective catalyst system for the allylation of vari...
Breglia, Raffaella Arrigoni, Federica Sensi, Matteo Greco, Claudio Fantucci, Piercarlo De Gioia, Luca Bruschi, Maurizio
Published in
Inorganic Chemistry
Density functional theory was used to investigate Ni,Fe-containing carbon monoxide dehydrogenase enzymes. Different coordination modes of the substrate CO2 to several forms and redox states of the C-cluster—the enzyme active site—were considered. The obtained results highlight the key role of the protein environment in tuning the reactivity and the...
Hoi, Julia K. Lieder, Barbara Liebisch, Beatrix Czech, Christiane Hans, Joachim Ley, Jakob P. Somoza, Veronika
Published in
ACS Omega
The cinnamon-derived bioactive aroma compound cinnamaldehyde (CAL) has been identified as a promising antiobesity agent, inhibiting adipogenesis and decreasing lipid accumulation in vitro as well as in animal models. Here, we investigated the antiadipogenic effect of cinnamyl isobutyrate (CIB), another cinnamon-derived aroma compound, in comparison...
