Liver disease is characterized by changes in all phases of hemostasis. These hemostatic alterations were long considered to predispose patients with liver disease towards a bleeding tendency, as they are associated with prolonged conventional coagulation tests. However, these patients may also suffer from thrombotic complications, and we now know t...
Goeijenbier, MarcoMeijers, Joost C MAnfasa, FatihRoose, Jeroen Mvan de Weg, Cornelia A MBakhtiari, KamranHenttonen, HeikkiVaheri, AnttiOsterhaus, Albert D M Evan Gorp, Eric C M
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Puumala virus (PUUV) infection causes over 5000 cases of hemorrhagic fever in Europe annually and can influence the hemostatic balance extensively. Infection might lead to hemorrhage, while a recent study showed an increased risk of myocardial infarction during or shortly after PUUV infection. The mechanism by which this hantavirus influences the c...
