Jantzen, Alexandra E Noviani, Maria Mills, James S Baker, Katherine M Lin, Fu-Hsiung Truskey, George A Achneck, Hardean E
Published in
Journal of biomedical materials research. Part B, Applied biomaterials
Nitinol-based vascular devices, for example, peripheral and intracranial stents, are limited by thrombosis and restenosis. To ameliorate these complications, we developed a technology to promote vessel healing by rapidly seeding (QuickSeeding) autologous blood-derived endothelial cells (ECs) onto modified self-expanding nitinol stent delivery syste...
Carter, Bing Z Andreeff, Michael
Published in
Oncoscience
Agarwal, Supreet Hynes, Paul G Tillman, Heather S Lake, Ross Abou-Kheir, Wassim G Fang, Lei Casey, Orla M Ameri, Amir H Martin, Philip L Yin, Juan Juan
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Published in
Cell reports
Primary prostate cancer almost always has a luminal phenotype. However, little is known about the stem/progenitor properties of transformed cells within tumors. Using the aggressive Pten/Tp53-null mouse model of prostate cancer, we show that two classes of luminal progenitors exist within a tumor. Not only did tumors contain previously described mu...
Yang, Ce Yang, Xuetao Du, Juan Wang, Haiyan Li, Haisheng Zeng, Ling Gu, Wei Jiang, Jianxin
Published in
Respiratory Research
BackgroundThe treatment of acute respiratory distress syndrome (ARDS), most commonly seen during the organ dysfunction remains unsatisfied. Presently, the stem/progenitor cell-based endogenous repair has been aroused attention enormously. This report investigated the effects of retinoic acid (RA) plus simvastatin (SS) with respect to dynamics of lu...
Aure, M H Arany, S Ovitt, C E
Published in
Journal of dental research
Understanding the intrinsic potential for renewal and regeneration within a tissue is critical for the rational design of reparative strategies. Maintenance of the salivary glands is widely thought to depend on the differentiation of stem cells. However, there is also new evidence that homeostasis of the salivary glands, like that of the liver and ...
Masuda, Hirotaka Maruyama, Tetsuo Gargett, Caroline E Miyazaki, Kaoru Matsuzaki, Yumi Okano, Hideyuki Tanaka, Mamoru
Published in
Biology of reproduction
Uterine endometrium is one of the most important organs for species preservation. However, the physiology of human endometrium remains poorly understood, because the human endometrium undergoes rapid and large changes during each menstrual cycle and it is very difficult to investigate human endometrium as one organ. This remarkable regenerative cap...
Krontiras, Panagiotis Gatenholm, Paul Hägg, Daniel A
Published in
Journal of biomedical materials research. Part B, Applied biomaterials
There is an increased interest in developing adipose tissue for in vitro and in vivo applications. Current two-dimensional (2D) cell-culture systems of adipocytes are limited, and new methods to culture adipocytes in three-dimensional (3D) are warranted as a more life-like model to study metabolic diseases such as obesity and diabetes. In this stud...
Kim, I. I. Poveshchenko, O. V. Bondarenko, N. A. Lykov, A. P. Poveschenko, A. F. Khabarov, D. V. Pokushalov, E. A. Romanov, A. B. Karaskov, A. M. Konenkov, V. I.
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Published in
Bulletin of Experimental Biology and Medicine
We studied the phenotype and cytokine production in peripheral blood mononuclear cells mobilized from the bone marrow after administration of granulocyte colony-stimulating factor (G-CSF) and the relationship of these parameters with clinical efficacy of autologous intramyocardial injection of donor cells in patients with chronic heart failure. We ...
Sîrbulescu, Ruxandra F Ilieş, Iulian Zupanc, Günther K H
Published in
Developmental neurobiology
Neural stem/progenitor cells in the neurogenic niches of the adult brain are widely assumed to give rise predominantly to neurons, rather than glia. Here, we performed a quantitative analysis of the resident neural progenitors and their progeny in the adult pacemaker nucleus (Pn) of the weakly electric fish Apteronotus leptorhynchus. Approximately ...
Maruyama, Tetsuo
Published in
The journal of obstetrics and gynaecology research
Human endometrium regenerates and regresses with each menstrual cycle under hormonal control throughout a woman's reproductive life. The cyclical regeneration and remodeling potentials allude to the existence of stem/progenitor cells in the endometrium. There is increasing evidence that human endometrium contains small numbers of stem-like cells ca...
