Ieyasu, Hidetaka Takai, Yoshimi Kaibuchi, Kozo Sawamura, Makoto Nishizuka, Yasutomi
Published in
Biochemical and Biophysical Research Communications
When rabbit platelets were stimulated by platelet-activating factor (PAF), phosphatidylinositol disappeared rapidly and diacylglycerol was transiently accumulated. Concurrently, an endogenous protein with a molecular weight of about 40,000 (40K protein) was heavily phosphorylated and serotonin was released. These PAF-induced reactions were associat...
Bregman, M D Sander, D Meyskens, F L Jr
PGA1 and PGE1 reduced the plating efficiency and inhibited proliferation of Cloudman S-91 murine melanoma cells in a dose dependent manner, as assessed by their effects on colony formation in soft agar. PGF2α did not reduce plating efficiency but was as effective as PGA1 in raising cAMP and cGMP levels. This data suggests that the inhibition of Clo...
Bregman, M D Sander, D Meyskens, F L Jr
PGA1 and PGE1 reduced the plating efficiency and inhibited proliferation of Cloudman S-91 murine melanoma cells in a dose dependent manner, as assessed by their effects on colony formation in soft agar. PGF2α did not reduce plating efficiency but was as effective as PGA1 in raising cAMP and cGMP levels. This data suggests that the inhibition of Clo...
Bregman, M D Sander, D Meyskens, F L Jr
PGA1 and PGE1 reduced the plating efficiency and inhibited proliferation of Cloudman S-91 murine melanoma cells in a dose dependent manner, as assessed by their effects on colony formation in soft agar. PGF2α did not reduce plating efficiency but was as effective as PGA1 in raising cAMP and cGMP levels. This data suggests that the inhibition of Clo...
Bregman, M D Sander, D Meyskens, F L Jr
PGA1 and PGE1 reduced the plating efficiency and inhibited proliferation of Cloudman S-91 murine melanoma cells in a dose dependent manner, as assessed by their effects on colony formation in soft agar. PGF2α did not reduce plating efficiency but was as effective as PGA1 in raising cAMP and cGMP levels. This data suggests that the inhibition of Clo...
Bregman, M D Sander, D Meyskens, F L Jr
PGA1 and PGE1 reduced the plating efficiency and inhibited proliferation of Cloudman S-91 murine melanoma cells in a dose dependent manner, as assessed by their effects on colony formation in soft agar. PGF2α did not reduce plating efficiency but was as effective as PGA1 in raising cAMP and cGMP levels. This data suggests that the inhibition of Clo...
Bregman, M D Sander, D Meyskens, F L Jr
PGA1 and PGE1 reduced the plating efficiency and inhibited proliferation of Cloudman S-91 murine melanoma cells in a dose dependent manner, as assessed by their effects on colony formation in soft agar. PGF2α did not reduce plating efficiency but was as effective as PGA1 in raising cAMP and cGMP levels. This data suggests that the inhibition of Clo...
Bregman, M D Sander, D Meyskens, F L Jr
PGA1 and PGE1 reduced the plating efficiency and inhibited proliferation of Cloudman S-91 murine melanoma cells in a dose dependent manner, as assessed by their effects on colony formation in soft agar. PGF2α did not reduce plating efficiency but was as effective as PGA1 in raising cAMP and cGMP levels. This data suggests that the inhibition of Clo...
Bregman, M D Sander, D Meyskens, F L Jr
PGA1 and PGE1 reduced the plating efficiency and inhibited proliferation of Cloudman S-91 murine melanoma cells in a dose dependent manner, as assessed by their effects on colony formation in soft agar. PGF2α did not reduce plating efficiency but was as effective as PGA1 in raising cAMP and cGMP levels. This data suggests that the inhibition of Clo...
Bregman, M D Sander, D
PGA1 and PGE1 reduced the plating efficiency and inhibited proliferation of Cloudman S-91 murine melanoma cells in a dose dependent manner, as assessed by their effects on colony formation in soft agar. PGF2α did not reduce plating efficiency but was as effective as PGA1 in raising cAMP and cGMP levels. This data suggests that the inhibition of Clo...
