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Li, Yang Wang, Jin Yin, Jie Liu, Xinhua Yu, Minghang Li, Ting Yan, Han Wang, Xi
Published in
Oncotarget
Studies of Natural Killer (NK) cell cytotoxicity have mainly focused on the balance of activating and inhibitory receptors, signaling transduction, calcium influx, formation of immune synapse, and cytolytic degranulation. However, little is known about the chromatin state of NK cells and the impact of its changes during target recognition. In this ...
Shibata, Yukimasa Nishiwaki, Kiyoji
Published in
Worm
Maintenance of cell fates is essential for the development and homeostasis of multicellular organisms and involves the preservation of the expression status of selector genes that control many target genes. Epigenetic marks have pivotal roles in the maintenance of gene expression status, as occurs with methylation on lysine 27 of histone H3 (H3K27m...