Tembo, Maiwase Wozniak, Katherine L Bainbridge, Rachel E Carlson, Anne E
Published in
The Journal of biological chemistry
Transmembrane member 16A (TMEM16A) is a widely expressed Ca2+-activated Cl- channel with various physiological functions ranging from mucosal secretion to regulating smooth muscle contraction. Understanding how TMEM16A controls these physiological processes and how its dysregulation may cause disease requires a detailed understanding of how cellula...
Breiden, Bernadette Sandhoff, Konrad
Published in
Biological Chemistry
Drug-induced phospholipidosis is a lysosomal storage disorder characterized by excessive accumulation of phospholipids. Its cellular mechanism is still not well understood, but it is known that cationic amphiphilic drugs can induce it. These drugs have a hydrophilic amine head group that can be protonated in the endolysosomal compartment. As cation...
Platre, Matthieu Bayle, Vincent Armengot, Laia Bareille, Joseph Marques-Bueno, Maria Mar Creff, Audrey Maneta-Peyret, Lilly Fiche, Jean-Bernard Nollmann, Marcelo Miege, Christine
...
Yan, Li Zhang, Xinhou Han, Zhongming Pang, Jiayin Lambers, Hans Finnegan, Patrick M
Published in
The New phytologist
Plants respond to soil phosphorus (P) availability by adjusting leaf P among inorganic P (Pi) and organic P fractions (nucleic acids, phospholipids, small metabolites and a residual fraction). We tested whether phylogenetically divergent plants in a biodiversity hotspot similarly adjust leaf P allocation in response to P limitation by sampling alon...
Nguyen, Van Cam Nakamura, Yuki Kanehara, Kazue
Published in
The Plant journal : for cell and molecular biology
Unsaturation of membrane glycerolipid classes at their hydrophobic fatty acid tails critically affects the physical nature of the lipid molecule. In Arabidopsis thaliana, 7 fatty acid desaturases (FADs) differently desaturate each glycerolipid class in plastids and the endoplasmic reticulum (ER). Here, we showed that polyunsaturation of ER glycerol...
Moreau, Dimitri Vacca, Fabrizio Vossio, Stefania Scott, Cameron Colaco, Alexandria Paz Montoya, Jonathan Ferguson, Charles Damme, Markus Moniatte, Marc Parton, Robert G
...
Published in
EMBO reports
Most cells acquire cholesterol by endocytosis of circulating low-density lipoproteins (LDLs). After cholesteryl ester de-esterification in endosomes, free cholesterol is redistributed to intracellular membranes via unclear mechanisms. Our previous work suggested that the unconventional phospholipid lysobisphosphatidic acid (LBPA) may play a role in...
al-bakri, amal g. mahmoud, nouf n.
In this study, the photothermal-induced bactericidal activity of phospholipid-decorated gold nanorods (DSPE-AuNR) suspension against Pseudomonas aeruginosa planktonic and biofilm cultures was investigated. We found that the treatment of planktonic culture of Pseudomonas aeruginosa with DSPE-AuNR suspension (0.25&ndash / 0.03 nM) followed by a conti...
Xu, Na Shanbhag, Anuj G Li, Bo Angkuratipakorn, Thamonwan Decker, Eric A
Published in
Journal of agricultural and food chemistry
Phosphatidylethanolamine (PE) and phosphatidylserine (PS) have been shown to increase the antioxidant activity of α-tocopherol. This study investigated the ability of PE or PS to increase the antioxidant activity of different tocopherol homologues in bulk oil. In addition, the ability of a phospholipase-D-modified lecithin (high in PE) to increase ...
Alves, Eliana Melo, Tânia Barros, Madalena P. Domingues, M. Rosário M. Domingues, Pedro
Published in
Molecules
Olives ( Olea europaea L.) are classic ingredients in the Mediterranean diet with well-known health benefits, but their lipid composition has not been fully addressed. In this work, we characterised triacylglycerol (TAG) and polar lipid profiles of the olive pulp while using a complementary methodological approach that was based on solid-phase extr...
Giaever, Guri Lissina, Elena Nislow, Corey
Published in
Microbial cell (Graz, Austria)
Sulfur assimilation and the biosynthesis of methionine, cysteine and S-adenosylmethionine (SAM) are critical to life. As a cofactor, SAM is required for the activity of most methyltransferases (MTases) and as such has broad impact on diverse cellular processes. Assigning function to MTases remains a challenge however, as many MTases are partially r...
