Shiomi, Akifumi Nagao, Kohjiro Kasai, Hisae Hara, Yuji Umeda, Masato
Published in
Bioscience, biotechnology, and biochemistry
Fish cell lines are widely used for the studies of developmental biology, virology, biology of aging, and nutrition physiology. However, little is known about their physicochemical properties. Here, we report the phospholipid compositions and mechanical properties of cell membranes derived from freshwater, anadromous and marine fish species. Biophy...
Yamada, Takeshi Seto, Hideki
Published in
Frontiers in Chemistry
The dynamic behavior of hydration water in phospholipid membranes has been investigated to understand the relationship between water and biological molecules using various experimental techniques. Quasi-elastic neutron scattering (QENS) is an effective method for this purpose because the dynamic behaviors of both water and lipid molecules could be ...
Yang, Chao Wang, Xu Wang, Jianying Wang, Xuejie Chen, Weitao Lu, Na Siniossoglou, Symeon Yao, Zhongping Liu, Kai
Published in
Neuron
Axotomy alters several glycerolipid biosynthetic enzymes to regulate axon regeneration in both CNS and PNS neurons. Depleting neuronal lipin1 and DGAT to redirect lipid synthesis away from triglycerides and toward phospholipids promotes axon regeneration.
Albouery, Mayssa Buteau, Bénédicte Grégoire, Stéphane Cherbuy, Claire Pais de Barros, Jean-Paul Martine, Lucy Chain, Florian Cabaret, Stéphanie Berdeaux, Olivier Bron, Alain M.
...
Published in
Frontiers in Cellular and Infection Microbiology
Understanding the molecular mechanisms underlying the changes observed during aging is a prerequisite to design strategies to prevent age-related diseases. Aging is associated with metabolic changes, including alteration in the brain lipid metabolism. These alterations may contribute to the development of pathophysiological conditions. Modification...
Magnani, Jessie E Donn, Steven M
Published in
Current pediatric reviews
Respiratory distress is one of the most common clinical presentations in newborns requiring admission to a Neonatal Intensive Care Unit (NICU). Many of these infants develop respiratory distress secondary to surfactant deficiency, which causes an interstitial lung disease that can occur in both preterm and term infants. Pulmonary surfactant is a pr...
Goupy, Pascale Genot, Claude Hammaz, Faiza Halimi, Charlotte Caris-Veyrat, Catherine Borel, Patrick
Kwiatek, Joanna M Han, Gil-Soo Carman, George M
Published in
Biochimica et biophysica acta. Molecular and cell biology of lipids
In yeast and higher eukaryotes, phospholipids and triacylglycerol are derived from phosphatidate at the nuclear/endoplasmic reticulum membrane. In de novo biosynthetic pathways, phosphatidate is channeled into membrane phospholipids via its conversion to CDP-diacylglycerol. Its dephosphorylation to diacylglycerol is required for the synthesis of tr...
Breiden, Bernadette Sandhoff, Konrad
Published in
Biological Chemistry
Drug-induced phospholipidosis is a lysosomal storage disorder characterized by excessive accumulation of phospholipids. Its cellular mechanism is still not well understood, but it is known that cationic amphiphilic drugs can induce it. These drugs have a hydrophilic amine head group that can be protonated in the endolysosomal compartment. As cation...
Vitrac, Heidi Mallampalli, Venkata K P S Dowhan, William
Published in
The Journal of biological chemistry
Posttranslational modifications of proteins, such as phosphorylation and dephosphorylation, play critical roles in cellular functions through diverse cell signaling pathways. Protein kinases and phosphatases have been described early on as key regulatory elements of the phosphorylated state of proteins. Tight spatial and temporal regulation of prot...
Fauquignon, Martin Ibarboure, Emmanuel Carlotti, Stéphane Brûlet, Annie Schmutz, Marc Le Meins, Jean-François
Published in
Polymers
In the emerging field of hybrid polymer/lipid vesicles, relatively few copolymers have been evaluated regarding their ability to form these structures and the resulting membrane properties have been scarcely studied. Here, we present the synthesis and self-assembly in solution of poly(dimethylsiloxane)- block -poly(ethylene oxide) diblock copolymer...
