Wu, Hao Dai, Zhenfeng Liu, Xi Lin, Ming Gao, Zeyu Tian, Fang Zhao, Xin Sun, Yi Pu, Xiaoping
Published in
Frontiers in Pharmacology
Objectives: We aimed to evaluate the effect of Shenfu injection in a rat model of ischemic heart failure and explore its mechanism. Methods: A rat model of ischemic heart failure after myocardial infarction was established by ligating the left anterior descending coronary artery. Forty-eight hours after surgery, the rats were intraperitoneally admi...
Bhaduri, Satarupa Zhang, Huamin Erramilli, Satchal Cramer, William A
Published in
The Journal of biological chemistry
The photosynthetic cytochrome b 6 f complex, a homodimer containing eight distinct subunits and 26 transmembrane helices per monomer, catalyzes proton-coupled electron transfer across the thylakoid membrane. The 2.5-Å-resolution structure of the complex from the cyanobacterium Nostoc sp. revealed the presence of 23 lipid-binding sites per monomer. ...
Chhetri, Dhani Raj
Published in
Frontiers in Pharmacology
Myo -inositol has been established as an important growth-promoting factor of mammalian cells and animals. The role of myo -inositol as a lipotropic factor has been proven, in addition to its involvement as co-factors of enzymes and as messenger molecules in signal transduction. Myo -inositol deficiency leads to intestinal lipodystrophy in animals ...
Olatunya, Ayomadewa Mercy Omojola, Akinwale Akinpelu, Kolawole Akintayo, Emmanuel Temitope
Published in
Preventive Nutrition and Food Science
Vitamin E, phytosterol, and phospholipids are classes of lipids that are also referred to as nutraceuticals. These lipids are components of foods, which have nutritional as well as numerous other health benefits, and consumption has been shown to prevent certain deadly diseases. These compounds can only be obtained from plant products; there is the...
Wu, Hao Liu, Xi Gao, Ze-yu Dai, Zhen-feng Lin, Ming Tian, Fang Zhao, Xin Sun, Yi Pu, Xiao-ping
Published in
International Journal of Molecular Sciences
Radix Aconiti Lateralis Preparata (fuzi) is the processed product of Aconitum carmichaelii Debeaux tuber, and has great potential anti-myocardial infarction effects, including improving myocardial damage and energy metabolism in rats. However, the effects of Radix Aconiti Lateralis Preparata extracts in a rat model of myocardial infarction have not...
Barbosa, Antonio D. Lim, Koini Mari, Muriel Edgar, James R. Gal, Lihi Sterk, Peter Jenkins, Benjamin J. Koulman, Albert Savage, David B. Schuldiner, Maya
...
Published in
Developmental Cell
Membrane phospholipids can be used as fatty acyl donors for the synthesis of triacylglycerols by enzymes called PDATs. Barbosa et al. present evidence that, in response to nutrient signals, the yeast PDAT Lro1 is active at the inner nuclear membrane, providing a link between organelle membrane remodeling and lipid storage.
Yu, Kuai Jiang, Tao Cui, YuanYuan Tajkhorshid, Emad Hartzell, H. Criss
Published in
Proceedings of the National Academy of Sciences of the United States of America
ANO1 (TMEM16A) is a Ca2+-activated Cl− channel that regulates diverse cellular functions including fluid secretion, neuronal excitability, and smooth muscle contraction. ANO1 is activated by elevation of cytosolic Ca2+ and modulated by phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2]. Here, we describe a closely concerted experimental and computat...
Zhu, Dan Hayman, Alan Kebede, Biniam Stewart, Ian Chen, Gang Frew, Russell
Published in
Journal of agricultural and food chemistry
Infant formula (IF), regarded as the optimal substitute for human breast milk, is very important for infant growth and development. Phospholipids (PLs) are ubiquitous components of infant formula as they have good emulsifier properties in addition to their nutritional and biological functions. In this study, the PL contents in four different commer...
Furtado, Jeremy D. Beqari, Jorind Campos, Hannia
Published in
Nutrients
Total plasma fatty acids or those in cholesteryl ester and phospholipids are often used to reflect fatty acid intake in epidemiological studies, but their relative performance as biomarkers of intake has not been clearly evaluated within a single population. The assessment of fatty acids in plasma fractions is more labor intensive. Thus, their use ...
Shrivastava, Rahul Chng, Shu-Sin
Published in
The Journal of Biological Chemistry
The outer membrane (OM) of Gram-negative bacteria exhibits unique lipid asymmetry, with lipopolysaccharides (LPS) residing in the outer leaflet and phospholipids (PLs) in the inner leaflet. This asymmetric bilayer protects the bacterium against intrusion of many toxic substances, including antibiotics and detergents, yet allows acquisition of nutri...
