Ameline, Camille Bourgeois, Yann Vögtli, Felix Savola, Eevi Andras, Jason Engelstädter, Jan Ebert, Dieter
Published in
Molecular biology and evolution
Parasites are a major evolutionary force, driving adaptive responses in host populations. Although the link between phenotypic response to parasite-mediated natural selection and the underlying genetic architecture often remains obscure, this link is crucial for understanding the evolution of resistance and predicting associated allele frequency ch...
Pineaux, Maxime Merkling, Thomas Danchin, Etienne Hatch, Scott Duneau, David Blanchard, Pierrick Leclaire, Sarah
Published in
Molecular ecology
Genes of the major histocompatibility complex (MHC) play a pivotal role in parasite resistance, and their allelic diversity has been associated with fitness variations in several taxa. However, studies report inconsistencies in the direction of this association, with either positive, quadratic or no association being described. These discrepancies ...
Gobbin, Tiziana P Vanhove, Maarten P M Pariselle, Antoine Groothuis, Ton G G Maan, Martine E Seehausen, Ole
Published in
Journal of evolutionary biology
Parasites may have strong eco-evolutionary interactions with their hosts. Consequently, they may contribute to host diversification. The radiation of cichlid fish in Lake Victoria provides a good model to study the role of parasites in the early stages of speciation. We investigated patterns of macroparasite infection in a community of 17 sympatric...
Gobbin, T. P. Vanhove, M. P. M. Pariselle, Antoine Groothuis, T. G. G. Maan, M. E. Seehausen, O.
Parasites may have strong eco-evolutionary interactions with their hosts. Consequently, they may contribute to host diversification. The radiation of cichlid fish in Lake Victoria provides a good model to study the role of parasites in the early stages of speciation. We investigated patterns of macroparasite infection in a community of 17 sympatric...
Cornetti, Luca Hilfiker, Daniela Lemoine, Mélissa Tschirren, Barbara
Published in
Molecular ecology
Spatial variation in pathogen-mediated selection is predicted to influence the evolutionary trajectory of host populations and lead to spatial variation in their immunogenetic composition. However, to date few studies have been able to directly link small-scale spatial variation in infection risk to host immune gene evolution in natural, nonhuman p...
Fornuskova, Alena Bryja, Josef Vinkler, Michal Macholán, Miloš Piálek, Jaroslav
Published in
Ecology and evolution
Detailed investigation of variation in genes involved in pathogen recognition is crucial for understanding co-evolutionary processes between parasites and their hosts. Triggering immediate innate response to invading microbes, Toll-like receptors (TLRs) belong presently among the best-studied receptors of vertebrate immunity. TLRs exhibit remarkabl...
Winternitz, J C Minchey, S G Garamszegi, L Z Huang, S Stephens, P R Altizer, S
Published in
Proceedings. Biological sciences / The Royal Society
Understanding drivers of genetic diversity at the major histocompatibility complex (MHC) is vitally important for predicting how vertebrate immune defence might respond to future selection pressures and for preserving immunogenetic diversity in declining populations. Parasite-mediated selection is believed to be the major selective force generating...
Taylor, T B Buckling, A
Published in
Journal of evolutionary biology
Dispersal provides the opportunity to escape harm and colonize new patches, enabling populations to expand and persist. However, the benefits of dispersal associated with escaping harm will be dependent on the structure of the environment and the likelihood of escape. Here, we empirically investigate how the spatial distribution of a parasite influ...
Van Doorslaer, Wendy; 48848; Stoks, Robby; 34380; Jeppesen, Erik; De Meester, Luc; 8482;
Although several studies suggest the occurrence of microevolutionary responses that may allow local persistence of populations under global warming, rigorous experimental proof is lacking. Here, we combined the realism and rigid, replicated experimental design of a large-scale mesocosm study where populations of the zooplankter Simocephalus vetulus...
Reid, Jane M Arcese, Peter Keller, Lukas F Elliott, Kyle H Sampson, Laura Hasselquist, Dennis
Published in
Proceedings. Biological sciences / The Royal Society
The consequences of inbreeding for host immunity to parasitic infection have broad implications for the evolutionary and dynamical impacts of parasites on populations where inbreeding occurs. To rigorously assess the magnitude and the prevalence of inbreeding effects on immunity, multiple components of host immune response should be related to inbr...
