Published in Annals of Microbiology
Paenibacillus sabina strain JD2, a chitinolytic marine bacterium, was isolated from sea dumps collected at Sultanpur near Bhavnagar, India and its nutritional requirement for chitinase production was defined using statistical optimisation method. Effect of 8 different medium components on chitinase production byPaenibacillus sabina strain JD2 was s...
Published in Statistical Applications in Genetics and Molecular Biology
We propose an approximate distribution for the gapped local score of a two sequence comparison. Our method stands on combining an adapted scoring scheme that includes the gaps and an approximate distribution of the ungapped local score of two independent sequences of i.i.d. random variables. The new scoring scheme is defined on h-tuples of the sequ...
Published in Biochemical Pharmacology
Artemisinin loses its antimalarial activity on prolonged exposure to erythrocytes, especially α-thalassemic erythrocytes. In this report, we show that the major artemisinin-inactivating factor in cytosol of normal erythrocytes was heat-labile but a heat-stable factor from α-thalassemic cells also played a significant role in reducing artemisinin ef...
Published in Quality & Quantity
The main goal of both Bayesian model selection and classical hypotheses testing is to make inferences with respect to the state of affairs in a population of interest. The main differences between both approaches are the explicit use of prior information by Bayesians, and the explicit use of null distributions by the classicists. Formalization of p...
Published in Statistical Applications in Genetics and Molecular Biology
For testing multiple null hypotheses, the classical approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate (FWER), the probability of even one false rejection. In many applications, one might be willing to tolerate more than one false rejection provided the number of such case...
Motivation: A number of available program packages determine the significant enrichments and/or depletions of GO categories among a class of genes of interest. Whereas a correct formulation of the prob-lem leads to a single exact null distribution, these GO tools use a large variety of statistical tests whose denominations often do not clarify the ...
We propose an approximate distribution for the gapped local score of a two sequence comparison. Our method stands on combining an adapted scoring scheme that includes the gaps and an approximate distribution of the ungapped local score of two independent sequences of i.i.d. random variables. The new scoring scheme is defined on h-tuples of the sequ...
Published in Natural Hazards
The b-value of the Gutenberg–Richter’s frequency–magnitude relation and the p-value of the modified Omori law, which describes the decay rate of aftershock activity, were investigated for more than 500 aftershocks in the Aksehir-Afyon graben (AAG) following the 15 December 2000 Sultandagi–Aksehir and the 3 February 2002 Çay–Eber and Çobanlar earthq...
Published in pure and applied geophysics
We employed layered model joint hypocentral determination (JHD) with station corrections to improve location identification for the 26 January, 2001 Mw 7.7 Bhuj early and late aftershock sequence. We relocated 999 early aftershocks using the data from a close combined network (National Geophysical Research Institute, India and Center for Earthquake...
Published in Metrika
Multivariate one-sided hypothesis-testing problems are very common in clinical trials with multiple endpoints. The likelihood ratio test (LRT) and union-intersection test (UIT) are widely used for testing such problems. It is argued that, for many important multivariate one-sided testing problems, the LRT and UIT fail to adapt to the presence of su...
