Li, Yu-Jie Du, Wei-Jia Liu, Rui Zan, Gui-Ying Ye, Bing-Lu Li, Qian Sheng, Zhi-Hao Yuan, Ya-Wei Song, Yu-Jie Liu, Jing-Gen
...
Published in
CNS neuroscience & therapeutics
Anxiety disorders associated with pain are a common health problem. However, the underlying mechanisms remain poorly understood. We aimed to investigate the role of paraventricular nucleus (PVN)-central nucleus of the amygdala (CeA) oxytocinergic projections in anxiety-like behaviors induced by inflammatory pain. After inflammatory pain induction b...
Yadollahzadeh, Mahdi Rezaie, Nader Eskandari, Mohana Farrokhpour, Mohsen Azimi, Mehdi Farasatinasab, Maryam
Published in
Journal of intensive care medicine
Although the role of oxytocin in the pathophysiology of sepsis is still unknown, rising preclinical evidence suggests that oxytocin is possibly involved. However, no direct clinical studies have measured the levels of oxytocin during sepsis. In this preliminary study, the serum oxytocin levels were evaluated throughout the duration of sepsis. Twent...
Feldman, Ruth
Published in
Frontiers in Human Neuroscience
To initiate discussion on women in science, we begin with Gerald Edelman’s definition: “Science is imagination in the service of the verifiable truth,” which underscores “verifiability,” truth reached by evidence, as the pathway science charts to Truth. “Verifiability” is named after the Roman Goddess Veritas, the daughter of Cronos and the mother ...
Berendzen, Kristen M.
Published in
Frontiers in Neurology
The representation and demonstration of human values are intimately tied to our status as a social species. Humans are relatively unique in our ability to form enduring social attachments, characterized by the development of a selective bond that persists over time. Such relationships include the bonds between parents and offspring, pair bonds betw...
Kraus, Jakub Výborová, Eliška Silani, Giorgia
Published in
Frontiers in Psychiatry
Understanding the neurobiology of social reward processing is fundamental, holding promises for reducing maladaptive/dysfunctional social behaviors and boosting the benefits associated with a healthy social life. Current research shows that processing of social (vs. non-social) rewards may be driven by oxytocinergic signaling. However, studies in h...
Berget, Bente Vas, Judit Pedersen, Gunn Uvnäs-Moberg, Kerstin Newberry, Ruth C.
Published in
Frontiers in Psychology
Introduction Positive social interactions with farm animals may have therapeutic benefits on humans by increasing brain oxytocin secretion, as inferred from circulating oxytocin levels. The aim of this observational study was to investigate acute changes in human plasma oxytocin levels and state anxiety associated with interactions with dairy cows....
Korb, Diane Lopez, Remi Hörlin, Anne Laure Schmitz, Thomas Borie, Constance Sibony, Olivier
Published in
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
To compare the effectiveness of prophylactic carbetocin with prophylactic oxytocin for preventing severe postpartum hemorrhage (PPH) following vaginal delivery. This before and after cohort study took place between 2020 and 2021 in a university maternity hospital. In 2021, the protocol for PPH prevention immediately after vaginal delivery changed: ...
Eisenach, James C Curry, Regina S Houle, Timothy T
Published in
Pain medicine (Malden, Mass.)
Compare intrathecal oxytocin, 100 µg to placebo on ongoing neuropathic pain and mechanical hyperalgesia and allodynia. Randomized, controlled, double-blind cross-over. Clinical research unit. Individuals aged 18 to 70 years with neuropathic pain for at least 6 months. Individuals received intrathecal injections of oxytocin and saline, separated by ...
Danoff, Joshua S. Page, Emma A. Perkeybile, Allison M. Kenkel, William M. Yee, Jason R. Ferris, Craig F. Carter, C. Sue Connelly, Jessica J.
Published in
Frontiers in Genetics
The neurohormone oxytocin regulates many aspects of physiology primarily by binding to its receptor, the oxytocin receptor. The oxytocin receptor gene (Oxtr) has been shown to have alternative transcripts in the mouse brain which may each have different biological functions or be used in specific contexts. A popular animal model for studying oxytoc...
Castellano, Juan M Ariza-Jimenez, Ana B Tena-Sempere, Manuel
Published in
The Journal of clinical endocrinology and metabolism
