Sánchez-Lafuente, Carla L. Johnston, Jenessa N. Reive, Brady S. Scheil, Kaylene K. A. Halvorson, Ciara S. Jimenez, Mariana Colpitts, Darian Kalynchuk, Lisa E. Caruncho, Hector J.
Published in
Frontiers in Molecular Neuroscience
Introduction Treatment with the synaptic plasticity protein reelin has rapid antidepressant-like effects in adult corticosterone (CORT)-induced depressed rats, whether administered repeatedly or acutely. However, these effects remain unexplored in the context of post-partum depression (PPD). Methods This study investigated the antidepressant-like e...
Mizushima, Sakae G. Fujisawa, Takashi X. Takiguchi, Shinichiro Kumazaki, Hirokazu Tanaka, Shiho Tomoda, Akemi
Published in
Frontiers in Psychiatry
Tomescu, Miralena; Van der Donck, Stephanie; 107873; Perisanu, Emanuela; Berceanu, Alexandru; Alaerts, Kaat; 50412; Boets, Bart; 32380; Carcea, Ioana;
Oxytocin (OXT) modulates social behaviors. However, the administration of exogenous OXT in humans produces inconsistent behavioral changes, affecting future consideration of OXT as a treatment for autism and other disorders with social symptoms. Inter-individual variability in social functioning traits might play a key role in how OXT changes brain...
Caria, Andrea
Published in
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
Historical evidence from stimulation and lesion studies in animals and humans demonstrated a close association between the hypothalamus and typical and atypical socioemotional behavior. A central hypothalamic contribution to regulation of socioemotional responses was also provided indirectly by studies on oxytocin and arginine vasopressin. However,...
Edwards, Melise M. Nguyen, Ha K. Dodson, Andrew D. Herbertson, Adam J. Wolden-Hanson, Tami Wietecha, Tomasz A. Honeycutt, Mackenzie K. Slattery, Jared D. O’Brien, Kevin D. Graham, James L.
...
Published in
Frontiers in Endocrinology
Previous studies indicate that CNS administration of oxytocin (OT) reduces body weight in high fat diet-induced obese (DIO) rodents by reducing food intake and increasing energy expenditure (EE). We recently demonstrated that hindbrain (fourth ventricular [4V]) administration of OT elicits weight loss and elevates interscapular brown adipose tissue...
Procyshyn, Tanya L Dupertuys, Juliette Bartz, Jennifer A
Although the social role of oxytocin came to light due to sex-specific interactions such as mother-offspring bonding, current understanding of sex differences in the effects of oxytocin on human sociality is limited because of the predominance of all-male samples. With the increasing inclusion of females in intranasal oxytocin research, it is now p...
di Giacomo, Ester Andreini, Elena Santambrogio, Jacopo Arcara, Alberto Clerici, Massimo
Published in
Frontiers in Psychiatry
Background Borderline personality disorder (BPD) is a complex mental health condition marked by instability in mood, relationships, self-image, and behavior. Individuals with BPD often struggle with intense emotions, impulsivity, and maintaining stable relationships. Oxytocin, known as the "love hormone" or "bonding hormone," plays a crucial role i...
Sosnowski, Meghan J. Brosnan, Sarah F.
Published in
Frontiers in Endocrinology
A key goal of the field of endocrinology has been to understand the hormonal mechanisms that drive social behavior and influence reactions to others, such as oxytocin. However, it has sometimes been challenging to understand which aspects and influences of hormonal action are conserved and common among mammalian species, and which effects differ ba...
Nakajima, Daisuke Yamachi, Megumi Misaka, Shingen Shimomura, Kenju Maejima, Yuko
Published in
Frontiers in Endocrinology
Objective Aromatherapy is a holistic healing method to promote health and well-being by using natural plant extracts. However, its precise mechanism of action and influence on the endocrine system remains unclear. Since recent studies reported that a neuropeptide, oxytocin, can attenuate anxiety, we hypothesized that if oxytocin secretion is promot...
Szabó, Péter Bonet, Sara Hetényi, Roland Hanna, Dániel Kovács, Zsófia Prisztóka, Gyöngyvér Križalkovičová, Zuzana Szentpéteri, József
Published in
Frontiers in Physiology
Introduction This systematic review investigates the interplay between oxytocin and exercise; in terms of analgesic, anti-inflammatory, pro-regenerative, and cardioprotective effects. Furthermore, by analyzing measurement methods, we aim to improve measurement validity and reliability. Methods Utilizing PRISMA, GRADE, and MECIR protocols, we examin...
