Wang, Tan Wang, Erqian Chen, Huan Li, Ningning Min, Hanyi
Published in
Frontiers in Physiology
Purpose: To investigate the different tamponade effects of intravitreal silicone oil (SO) and perfluoropropane gas on the retinal structure and vasculature in proliferative diabetic retinopathy (PDR) patients. Methods: Thirty-eight eligible patients (47 eyes) with PDR requiring pars plana vitrectomy (PPV) were enrolled in the prospective observatio...
Paques, Michel Norberg, Nathaniel Chaumette, Céline Sennlaub, Florian Rossi, Ethan Borella, Ysé Grieve, Kate
Published in
Frontiers in Medicine
Geographic atrophy (GA), the late stage of age-related macular degeneration, is a major cause of visual disability whose pathophysiology remains largely unknown. Modern fundus imaging and histology revealed the complexity of the cellular changes that accompanies atrophy. Documenting the activity of the disease in the margins of atrophy, where the t...
sasajima;, hirofumi
We investigated whether baseline foveal intraretinal fluid (IRF) localization affects the visual prognosis of branch retinal vein occlusion (BRVO). Fifty eyes from 50 patients were included in this retrospective study. We classified the eyes with IRF involving and not involving the central foveola on the vertical optical coherence tomography (OCT) ...
popa-fotea;, nicoleta-monica
Ischemic heart disease is one of the most important causes of mortality and morbidity worldwide. Revascularization of coronary stenosis inducing ischemia, either by percutaneous or surgical intervention, significantly reduces major adverse cardiovascular events and improves quality of life. However, in cases of intermediate lesions, classified by a...
Ehlers, Justis P. Patel, Nikhil Kaiser, Peter K. Heier, Jeffrey S. Brown, David M. Meng, Xiangyi Reese, Jamie Lunasco, Leina Le, Thuy K. Hu, Ming
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Published in
Investigative Ophthalmology & Visual Science
Purpose To evaluate the association of fluid volatility with ellipsoid zone (EZ) integrity and subretinal hyperreflective material (SHRM) volume during anti–vascular endothelial growth factor (VEGF) therapy in neovascular age-related macular degeneration (nAMD). Methods This study was a post hoc analysis of the OSPREY study. Retinal volatility was ...
Monroy, Guillermo L. Fitzgerald, Sean T. Locke, Andrea Won, Jungeun Spillman, Jr., Darold R. Ho, Alexander Zaki, Farzana R. Choi, Honggu Chaney, Eric J. Werkhaven, Jay A.
...
Published in
Frontiers in Photonics
Otitis media (OM) is a common disease of the middle ear, affecting 80% of children before the age of three. The otoscope, a simple illuminated magnifier, is the standard clinical diagnostic tool to observe the middle ear. However, it has limited contrast to detect signs of infection, such as clearly identifying and characterizing middle ear fluid o...
Ai, Zhuang Huang, Xuan Feng, Jing Wang, Hui Tao, Yong Zeng, Fanxin Lu, Yaping
Published in
Frontiers in Neuroinformatics
Optical coherence tomography (OCT) is a new type of tomography that has experienced rapid development and potential in recent years. It is playing an increasingly important role in retinopathy diagnoses. At present, due to the uneven distributions of medical resources in various regions, the uneven proficiency levels of doctors in grassroots and re...
Guimarães, Pedro Serranho, Pedro Martins, João Moreira, Paula I. Ambrósio, António Francisco Castelo-Branco, Miguel Bernardes, Rui
Published in
Frontiers in Aging Neuroscience
The retina, as part of the central nervous system (CNS), can be the perfect target for in vivo, in situ, and noninvasive neuropathology diagnosis and assessment of therapeutic efficacy. It has long been established that several age-related brain changes are more pronounced in Alzheimer's disease (AD). Nevertheless, in the retina such link is still ...
Lu, Yiming Zhou, Hao Zhou, Xiao Chen, Yuxuan Wang, Ruikang K
Published in
Translational vision science & technology
To investigate the correlation between laser speckle flowgraphy (LSFG) signals and the quantitative metrics derived from optical coherence tomography (OCT) in normal eyes. LSFG, OCT, and OCT angiography (OCTA) imaging were performed on normal participants using a custom-designed LSFG system and a commercial swept-source OCT system. Mean (PWM) and a...
Ran, An Ran Wang, Xi Chan, Poemen P. Chan, Noel C. Yip, Wilson Young, Alvin L. Wong, Mandy O. M. Yung, Hon-Wah Chang, Robert T. Mannil, Suria S.
...
Published in
Frontiers in Medicine
Purpose We aim to develop a multi-task three-dimensional (3D) deep learning (DL) model to detect glaucomatous optic neuropathy (GON) and myopic features (MF) simultaneously from spectral-domain optical coherence tomography (SDOCT) volumetric scans. Methods Each volumetric scan was labelled as GON according to the criteria of retinal nerve fibre lay...