Kandurova, K. Yu. Potapova, E. V. Zherebtsov, E. A. Dremin, V. V. Seryogina, E. S. Vinokurov, A. Yu. Mamoshin, A. V. Borsukov, A. V. Ivanov, Yu. V. Dunaev, A. V.
...
Published in
Optics and Spectroscopy
AbstractA device for optical biopsy with a fluorescence spectroscopy channel and a fine-needle optical probe for use in fine-needle aspiration biopsy of liver tumors is described. To test the developed device, experimental measurements of the fluorescence of internal organs of a laboratory rat were carried out in vivo while exposing the tissue surf...
Nie, Zhaojun Yeh, Shu-Chi Allison LePalud, Michelle Badr, Fares Tse, Frances Armstrong, David Liu, Louis W. C. Deen, M. Jamal Fang, Qiyin
Published in
Frontiers in Physiology
Screening and surveillance for gastrointestinal (GI) cancers by endoscope guided biopsy is invasive, time consuming, and has the potential for sampling error. Tissue endogenous fluorescence spectra contain biochemical and physiological information, which may enable real-time, objective diagnosis. We first briefly reviewed optical biopsy modalities ...
Jerjes, Waseem Hamdoon, Zaid Hopper, Colin
Published in
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
In this immediate ex vivo study, we aimed to identify the structures of normal and pathological facial skin using optical coherence tomography (OCT) and compared them to the gold standard histopathology. A total of 53 patients, with 57 suspicious facial lesions, participated in this study. A set of variables have been highlighted by the pathologist...
Paasch, Uwe Said, Tamer
Published in
Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology
Introduction: Induction of collagen and elastin remodeling in the human skin can be achieved by non-ablative fractional laser (NAFXL) and ablative fractional laser (AFXL). Our objective was to compare the safety, efficacy, tolerability, and ability to induce collagen and elastin remodeling of NAFXL versus AFXL in a series of treatments over time.Ma...
Ross, Calum A. MacLachlan, David G. Smith, Brian J. E. Beck, Rainer J. Shephard, Jonathan D. Weston, Nick Thomson, Robert R.
Published in
Micromachines
Optical biopsy describes a range of medical procedures in which light is used to investigate disease in the body, often in hard-to-reach regions via optical fibres. Optical biopsies can reveal a multitude of diagnostic information to aid therapeutic diagnosis and treatment with higher specificity and shorter delay than traditional surgical techniqu...
Zeng, Yifeng Xu, Shiqi Chapman, William C Jr Li, Shuying Alipour, Zahra Abdelal, Heba Chatterjee, Deyali Mutch, Matthew Zhu, Quing
Published in
Theranostics
Prior reports have shown optical coherence tomography (OCT) can differentiate normal colonic mucosa from neoplasia, potentially offering an alternative technique to endoscopic biopsy - the current gold-standard colorectal cancer screening and surveillance modality. To help clinical translation limited by processing the large volume of generated dat...
Favreau, Peter F Deal, Joshua A Harris, Bradley Weber, David S Rich, Thomas C Leavesley, Silas J
Published in
Journal of biophotonics
Spectral imaging approaches provide new possibilities for measuring and discriminating fluorescent molecules in living cells and tissues. These approaches often employ tunable filters and robust image processing algorithms to identify many fluorescent labels in a single image set. Here, we present results from a novel spectral imaging technology th...
Zhou, Yan Liu, Cheng-Hui Wu, Binlin Yu, Xinguang Cheng, Gangge Zhu, Ke Wang, Kai Zhang, Chunyuan Zhao, Mingyue Zong, Rui
...
Published in
Journal of biomedical optics
Glioma is one of the most refractory types of brain tumor. Accurate tumor boundary identification and complete resection of the tumor are essential for glioma removal during brain surgery. We present a method based on visible resonance Raman (VRR) spectroscopy to identify glioma margins and grades. A set of diagnostic spectral biomarkers features a...
Chen, Si Ge, Xin Liu, Xinyu Ding, Qianshan Wang, Nanshuo Wang, Xianghong Chen, Shufen Liang, Haitao Deng, Yunchao Xiong, Qiaozhou
...
Published in
Bioengineering & translational medicine
Detecting early-stage epithelial cancers and their precursor lesions are challenging as lesions could be subtle and focally or heterogeneously distributed over large mucosal areas. Optical coherence tomography (OCT) that enables wide-field imaging of subsurface microstructures in vivo is a promising screening tool for epithelial diseases. However, ...
Zhou, Yan Liu, Cheng-Hui Wu, Binlin Yu, Xinguang Cheng, Gangge Zhu, Ke Wang, Kai Zhang, Chunyuan Zhao, Mingyue Zong, Rui
...
Glioma is one of the most refractory types of brain tumor. Accurate tumor boundary identification and complete resection of the tumor are essential for glioma removal during brain surgery. We present a method based on visible resonance Raman (VRR) spectroscopy to identify glioma margins and grades. A set of diagnostic spectral biomarkers features a...
