Stent, G S
Published in
Proceedings of the National Academy of Sciences of the United States of America
Hebb's postulate of learning envisages that activation or inactivation of extant synaptic contacts in plastic neural networks depends on the synchronous impulse activity of pre- and postsynaptic nerve cells. The physiological mechanism proposed here for this process posits that at synapses acting according to Hebb's postulate, the receptors for the...
Klee, Werner A. Nirenberg, Marshall
Published in
Proceedings of the National Academy of Sciences of the United States of America
A neuroblastoma × glioma hybrid cell line with well-developed neural properties was found that has high-affinity morphine receptors. The average cell contains approximately 3 × 106 receptors. In contrast, parent cells and other neuroblastoma or hybrid cell lines tested had few or no morphine receptors.
Kriegstein, Arnold R. Castellucci, Vincent Kandel, Eric R.
Published in
Proceedings of the National Academy of Sciences of the United States of America
To utilize the advantages offered by the large identified nerve cells of the marine mollusc Aplysia californica for cellular biological studies of development, we have devised simple techniques for growing this species in the laboratory in large number with a generation time as short as nineteen weeks. We have used the cultured animals to study the...
Riddle, D L
Published in
Journal of nematology
The current genetic research on Caenorhabditis elegans and the application of genetic techniques to the analysis of development and behavior in this animal are reviewed. Some aspects of the work are emphasized more than others and this inevitably reflects the author's own interests and prejudices. An effort was made to point out the advantages that...
Rutherford, T A Croll, N A
Published in
Journal of nematology
The wave forms and activity patterns of Caenorhabditis elegans were examined on agar in the presence of known chemical attractants (NaCl) and repellents (D-tryptophan), and in thermal gradients. Total activity was reduced in both attractants and repellents. Different combinations of transfers between chemicals were investigated. Two thresholds were...
Amunts, K. Istomin, V.
As a powerful approach to the image processing, the Mathematical Morphology (MM) proved the advantages of its application in many different fields, including biomedical disciplines. In the previous paper we gave an overview of the morphocorticography method, its main principles and some applications in neuroscience. Thereby, the exploitation of MM ...
Amunts, K. Istomin, V.
For more than ten years attempts have been made to apply automatic procedures for exploration of cortical cytoarchitectonics. Investigations of human and pigs brains were carried out by a method described as "automatic morphocorticography". In the result of image analysis we got a set of parameter curves reflecting AREA-specific, individual, ontoge...
Vetter, Thomas Poggio, Tomaso B'ulthoff, Heinrich
Many 3D objects in the world around us are strongly constrained. For instance, not only cultural artifacts but also many natural objects are bilaterally symmetric. Thoretical arguments suggest and psychophysical experiments confirm that humans may be better in the recognition of symmetric objects. The hypothesis of symmetry-induced virtual views to...
Beteta Pacheco, Edmundo
Through an attractive hypothesis of work, we present the relaTionship between the frontal lobes and the neurobiological bases of Freud's psychoanalytic theory. We review and discuss the psycophysiological and clinical aproachs, in order to understand this relationship, arriving to the final examination of the organic and functional "disolutions" of...
Grossman, Robert Yehuda, Rachel Boisoneau, David Schmeidler, James Giller, Earl L. Jr.
Published in
Biological Psychiatry
The prolactin and cortisol responses to dexamethasone (0.5 mg) were studied in combat veterans with ( n = 18) and without ( n = 12) posttraumatic stress disorder (PTSD) and normal controls ( n = 18). Both veteran groups demonstrated greater prolactin suppression than the normals. In contrast, only veterans with PTSD showed an enhanced cortisol supp...