Chen, Gui-Dong Cao, Bin-Xiao Shi, Ying Lv, Jie-Min Wang, Dong-Hai Shi, Lun-Bo
Published in
Journal of chemotherapy (Florence, Italy)
The neoadjuvant chemotherapy plays an important role in locally advanced gastric cancer, but its efficacy, safety profiles and clinical outcomes among different regimens still remain controversial. In this study, totally 231 eligible patients with locally advanced gastric cancer were enrolled. These patients were divided into the observation group ...
Li, Yuanyuan Dong, Bingbin Wu, Wei Wang, Jiawei Jin, Hao Chen, Kangmei Huang, Kangling Huang, Songyin Yao, Yandan
Published in
Frontiers in Oncology
Background Growing evidence supports the modulatory role of human gut microbiome on neoadjuvant chemotherapy (NAC) efficacy. However, the relationships among the gut microbiome, tumor-infiltrating lymphocytes (TILs), and NAC response for breast cancer (BC) patients remain unclear. We thus proposed this preliminary study to investigate the relations...
Ono, Ayaka Murakami, Yuji Abdel-Wahab, May Nagata, Yasushi
Published in
Journal of gastrointestinal oncology
Borderline resectable pancreatic cancer (BRPC) is a tumor that infiltrates into the large blood vessels, with a high probability that the tumor will remain after surgical resection. To date, there has been no confirmed treatment strategy for BRPC. However, high-level studies, such as those using the intention-to-treat analysis, have recently been p...
Lee, Jeeyeon Park, Nora Jee-Young Kang, Byeongju Jung, Jin Hyang Kim, Wan Wook Chae, Yee Soo Lee, Soo Jung Kim, Hye Jung Park, Ji-Young Park, Ho Yong
...
Published in
Frontiers in Surgery
Background The American Joint Committee on Cancer (AJCC) guideline recommends the evaluation of ≥10 axillary lymph nodes (ALN) in patients with breast cancer to assess the N stage. However, the total ALN count in ALN dissection (ALND) often decreases after neoadjuvant chemotherapy in breast cancer. The authors compared clinicopathological factors a...
Huang, Yibao Zhu, Qingqing Xue, Liru Zhu, Xiaoran Chen, Yingying Wu, Mingfu
Published in
Frontiers in Oncology
The clinical benefit of neoadjuvant chemotherapy (NACT) before concurrent chemoradiotherapy (CCRT) vs. adjuvant chemotherapy after CCRT is debated. Non-response to platinum-based NACT is a major contributor to poor prognosis, but there is currently no reliable method for predicting the response to NACT (rNACT) in patients with locally advanced cerv...
Zhu, Yongjian Jiang, Zhichao Wang, Bingzhi Li, Ying Jiang, Jun Zhong, Yuxin Wang, Sicong Jiang, Liming
Published in
Frontiers in Oncology
Background This study aimed to explore the predictive value of quantitative dynamic contrast-enhanced MRI (DCE-MRI) and intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) quantitative parameters for the response to neoadjuvant chemotherapy (NCT) in locally advanced gastric cancer (LAGC) patients, and the relationship between the pre...
Lawton, Frank G Pavlik, Edward J
Published in
Diagnostics (Basel, Switzerland)
Unlike many other malignancies, overall survival for women with epithelial ovarian cancer has improved only modestly over the last half-century. The perspectives presented here detail the views of a gynecologic oncologist looking back and the view of the academic editor looking forward. Surgical beginnings in 1809 are merged with genomics, surgical...
Peng, Yunsong Cheng, Ziliang Gong, Chang Zheng, Chushan Zhang, Xiang Wu, Zhuo Yang, Yaping Yang, Xiaodong Zheng, Jian Shen, Jun
...
Published in
Frontiers in Oncology
Purpose To compare the performances of deep learning (DL) to radiomics analysis (RA) in predicting pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) based on pretreatment dynamic contrast-enhanced MRI (DCE-MRI) in breast cancer. Materials and Methods This retrospective study included 356 breast cancer patients who underwent DCE...
Tao, Yin Tang, Xue-Ting Li, Xing Wu, An-Shan Zhou, Hou-Shen Zhou, Cheng-fang
Published in
Frontiers in Medicine
Objective This study evaluated the role of neoadjuvant chemotherapy (NACT) with bevacizumab intraperitoneal perfusion in advanced ovarian cancer (AOC). Methods In this study, 80 patients with advanced epithelial ovarian cancer (stage IIIc or IV) who received NACT at the Central Hospital of Zhuzhou between February 2019 and October 2020 were enrolle...
Chen, Li Kong, Xiangyi Huang, Shaolong Su, Zhaohui Zhu, Mengliu Fang, Yi Zhang, Lin Li, Xingrui Wang, Jing
Published in
Frontiers in Immunology
Objective This study aims at investigating the potential prognostic significance of the breast immune prognostic index (BIPI) in breast cancer patients who received neoadjuvant chemotherapy (NACT). Methods The optimal cutoff value was calculated through the receiver operating characteristic curve (ROC). The correlations between BIPI and clinicopath...
