Jin, Xiaoli Sun, Hongcun Jiang, Wenbo
Published in
American Journal of Translational Research
Objective: To explore the influence of a systematic nursing mode on the quality of life and pain of patients with chronic sinusitis and nasal polyps (CSNP) after endoscopic sinus surgery. Methods: In this prospective study, a total of 114 patients with CSNP who were admitted to our hospital were randomly divided into an observation group (n=57) and...
Du, Kun Wang, Min Zhang, Nan Yu, Pei Wang, Ping Li, Ying Wang, Xiangdong Zhang, Luo Bachert, Claus
Published in
Clinical and translational allergy
Tissue remodeling caused by increased MMPs is involved in the pathogenesis of chronic rhinosinusitis with nasal polyposis (CRSwNP). We previously found higher levels of periostin and tenascin C in CRSwNPs, but whether they are associated with the dysregulation of MMPs is unknown. Therefore, the present study aimed to investigate the regulatory role...
C Morse, Justin Miller, Craig Senior, Brent
Published in
Journal of asthma and allergy
Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a phenotypic designation of the broader condition of chronic rhinosinusitis. The advent of targeted biologics has shown promise in targeting different aspects of the inflammatory pathway, yet there remains a lack of consensus on the correct timing and use of these medications. This review seek...
Deng, Huiyi Li, Meijiao Zheng, Rui Qiu, Huijun Yuan, Tian Wang, Weihao Yang, Qintai Long, Zijie Huang, Xuekun
Published in
Journal of asthma and allergy
Hippo-Yes-associated protein (YAP) pathway plays an important role in epithelial cell proliferation and inflammation development in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the underlying mechanisms remain unclear. This study intends to investigate the role of YAP and the nuclear factor kappa-B (NF-κB) pathway in cell proliferati...
Chauhan, Khushboo Sharma, Tanya Sharma, Bhavana Karkhur, Samendra
Published in
BMJ case reports
A 37-year-old Indian female presented with forward protrusion of left eye for one week, associated with progressive diminution of vision. The patient had undergone sinus surgery for nasal polyposis a year ago. On examination, there was severe proptosis and limitation of extraocular movements in all gazes. CT-scan revealed a heterogeneous expansile ...
Martens, Katleen De Boeck, Ilke Jokicevic, Katarina Kiekens, Filip Farré, Ricard Vanderveken, Olivier M Seys, Sven F Lebeer, Sarah Hellings, Peter W Steelant, Brecht
...
Published in
Allergy, asthma & immunology research
A defective epithelial barrier has been demonstrated in chronic rhinosinusitis with nasal polyps (CRSwNP). Lactobacilli are shown to restore epithelial barrier defects in gastrointestinal disorders, but their effect on the airway epithelial barrier is unknown. In this study, hence, we evaluated whether the nasopharyngeal isolates Lacticaseibacillus...
Armengot-Carceller, Miguel Gómez-Gómez, María José García-Navalón, Carmen Doménech-Campos, Encarna Muñoz-Fernández, Noelia Miguel, Ainhoa García-Lliberós de Marco-Algarra, Jaime Palop-Cervera, Marta Piñero, Alfonso García
Published in
American journal of rhinology & allergy
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a clinical entity with specific features that impacts significantly on patient quality of life (QoL). CRSwNP is often associated with asthma and is difficult to control and manage despite pharmacological and/or surgical treatment. Omalizumab, a monoclonal anti-IgE antibody, has emerged as a putat...
Kim, Yi Sook Han, Dohyun Mo, Ji Hun Kim, Yong Min Kim, Dae Woo Choi, Hyo Guen Park, Jong Wan Shin, Hyun Woo
Published in
Allergy, asthma & immunology research
Chronic rhinosinusitis (CRS) is a heterogeneous chronic inflammatory condition of the paranasal sinuses and nasal passages. Although antibiotics are used to reduce inflammation or to treat an episode of acute rhinosinusitis, their effects on the nasal environment and host response in CRS is unclear. We analyzed the effects of antibiotics on the nas...
Vlaminck, Stephan Acke, Frederic Prokopakis, Emmanuel Speleman, Kato Kawauchi, Hideyuki van Cutsem, Jean-Christophe Hellings, Peter W Jorissen, Mark Seys, Sven Bachert, Claus
...
Published in
American journal of rhinology & allergy
Chronic rhinosinusitis with nasal polyps (CRSwNP) often requires surgery, but recurrence even after surgery is common. Recurrence rates largely vary in literature and asthma seems to be a comorbid factor. In this study, we aim to estimate disease recurrence during a long-term follow-up, together with the investigation of possible predicting and/or ...
Cook, Kevin A Domissy, Alain Simon, Ronald A White, Andrew A Modena, Brian D
Published in
International forum of allergy & rhinology
