Inoue, Shinya Takata, Takanobu Nakazawa, Yusuke Nakamura, Yuka Guo, Xin Yamada, Sohsuke Ishigaki, Yasuhito Takeuchi, Masayoshi Miyazawa, Katsuhito
Published in
Nutrients
Excessive intake of glucose and fructose in beverages and foods containing high-fructose corn syrup (HFCS) plays a significant role in the progression of lifestyle-related diseases (LSRD). Glyceraldehyde-derived advanced glycation end-products (AGEs), which have been designated as toxic AGEs (TAGE), are involved in LSRD progression. Understanding o...
Almanza-Aguilera, Enrique Hernáez, Álvaro Corella, Dolores Sanllorente, Albert Ros, Emilio Portolés, Olga Valussi, Julieta Estruch, Ramon Coltell, Oscar Subirana, Isaac
...
Published in
Journal of Clinical Medicine
We aimed to explore the differences in the whole transcriptome of peripheral blood mononuclear cells between elderly individuals with and without type 2 diabetes (T2D). We conducted a microarray-based transcriptome analysis of 19 individuals with T2D and 15 without. Differentially expressed genes according to linear models were submitted to the Ing...
Bae, Heekyong R. Choi, Myung-Sook Kim, Suntae Young, Howard A. Gershwin, M. Eric Jeon, Seon-Min Kwon, Eun-Young
Published in
International Journal of Molecular Sciences
Obesity, a characteristic of metabolic syndrome, is also associated with chronic inflammation and the development of autoimmune diseases. However, the relationship between obesity and autoimmune diseases remains to be investigated in depth. Here, we compared hepatic gene expression profiles among high-fat diet (HFD) mice using the primary biliary c...
LIN, SHENG YANG, LIU WANG, SHIBIAO WENG, BIN LIN, MIN
Published in
Polish Journal of Microbiology
To clarify crucial key micro-RNAs and mRNAs associated with hand, foot, and mouth disease (HFMD) virus infection, we conducted this bioinformatics analysis from four GEO datasets. The following datasets were used for the analysis: GSE85829, GSE94551, GSE52780, and GSE45589. Differentially expressed genes (DEGs) were acquired, and the analysis of fu...
Marques, Nathália S A A Silva, Israel G Sales da Cavalcanti, Davi L Maia, Patrícia C S V Santos, Vanessa P Andrade, Rosileide F S Campos-Takaki, Galba M
Published in
Biomolecules
The successful production of a biosurfactant is dependent on the development of processes using low cost raw materials. In the present work, an economically attractive medium composed of corn steep liquor and waste cooking oil was formulated to maximize the production of bioemulsifier by Mucor circinelloides UCP0001. A central rotational composite ...
Sun, Wei Han, Bo Cai, Dongxiao Wang, Jing Jiang, Diandong Jia, Hailin
Published in
Frontiers in Molecular Biosciences
Circular RNAs (circRNAs) have emerged as essential regulators and biomarkers in various diseases. To assess the different expression levels of circRNAs in pediatric dilated cardiomyopathy (PDCM) and explore their biological and mechanistic significance, we used RNA microarrays to identify differentially expressed circRNAs between three children dia...
Zhou, Peipei He, Jinxu Huang, Lu Yu, Ziming Su, Zhenning Shi, Xuetao Zhou, Jianhua
Published in
Nanomaterials
High-throughput screening is a potent technique to accelerate the discovery and development of new materials. By performing massive synthesis and characterization processes in parallel, it can rapidly discover materials with desired components, structures and functions. Among the various approaches for high-throughput screening, microfluidic platfo...
Ma, Minxing Han, Guoxiong Wang, Yi Zhao, Ziyan Guan, Feng Li, Xiang
Published in
Aging (Albany NY)
Dysregulation of α(1,6)-fucosyltransferase (FUT8) plays significant roles in development of a variety of malignant tumor types. We collected as many relevant articles and microarray datasets as possible to assess the prognostic value of FUT8 expression in malignant tumors. For this purpose, we systematically searched PubMed, Embase, Web of Science,...
Morris, Robert Armbruster, Kyle Silva, Julianna Widell, Daniel James Cheng, Feng
Published in
Brain Sciences
The degenerative cognitive and physical decline of Alzheimer patients, coupled with the extensive psychological and economic tolls imposed on family members that serve as caretakers, necessitate the discovery of effective cures and preventative measures for age-related cognitive depreciation. In the journey of Alzheimer’s disease treatment discover...
Lin, Shenglong Lin, Minghua Ma, Huaxi Wang, Xiangmei Zhang, Dongqing Wu, Wenjun Lin, Jiahuang Gao, Haibing
Published in
Experimental and Therapeutic Medicine
Hepatitis B virus-related liver cirrhosis (HBV-LC) is susceptible to bacterial infections, which could lead to adverse prognosis in patients. MicroRNAs (miRs/miRNAs) are easily detected in peripheral blood and are involved in multiple liver diseases. The present pilot study aimed to investigate differentially expressed (DE) miRNAs in the serum of p...