Psychoactive plants and fungi: biochemistry and genomics
Published in Frontiers in Plant Science
Psychoactive plants and fungi: biochemistry and genomics
Plant-microbe omics
Published in Frontiers in Analytical Science
Omics and its integration: a systems biology approach to understanding plant physiology
Published in Frontiers in Plant Science
Serum, spleen metabolomics and gut microbiota reveals effect of catalpol on blood deficiency syndrome caused by cyclopho...
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Published in Frontiers in Immunology
Catalpol (CA), extracted from Rehmannia Radix, holds extensive promise as a natural medicinal compound. This study employed 16S rRNA gene sequencing and combined serum and spleen metabolomics to profoundly investigate the therapeutic effects of CA on blood deficiency syndrome (BDS) and the underlying mechanisms. Notably, CA exhibited effectiveness ...
Serum Metabolomic Profiles for Distinguishing Lung Cancer From Pulmonary Tuberculosis: Identification of Rapid and Nonin...
...Published in The Journal of infectious diseases
Pulmonary tuberculosis (PTB) and lung cancer (LC) have similar clinical symptoms and atypical imaging findings, which are easily misdiagnosed. There is an urgent need for a noninvasive and accurate biomarker to distinguish LC from PTB. A total of 694 subjects were enrolled and divided into discovery set (n = 122), identification set (n = 214), and ...
Molecular Characterization of Cooking Processes: A Metabolomics Decoding of Vaporous Emissions for Food Markers and Ther...
Published in Journal of agricultural and food chemistry
Thermal processing of food plays a fundamental role in everyday life. Whereas most researchers study thermal processes directly in the matrix, molecular information in the form of non- and semivolatile compounds conveyed by vaporous emissions is often neglected. We performed a metabolomics study of processing emissions from 96 different food items ...
Transcriptomics and metabolomics reveal the primary and secondary metabolism changes in Glycyrrhiza uralensis with diffe...
Published in Frontiers in Plant Science
The roots and rhizomes of Glycyrrhiza uralensis Fisch. represent the oldest and most frequently used herbal medicines in Eastern and Western countries. However, the quality of cultivated G. uralensis has not been adequate to meet the market demand, thereby exerting increased pressure on wild G. uralensis populations. Nitrogen, vital for plant growt...
Integrative metabolomic and network pharmacological analysis reveals potential mechanisms of Cardamine circaeoides Hook....
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Published in Frontiers in Pharmacology
The fabrication of bone tissue engineering scaffolds including bioactive factors by low-temperature deposition manufacturing and its application for bone defect repair.
Identification of Differential Metabolites Between Type 2 Diabetes and Postchronic Pancreatitis Diabetes (Type 3c) Based...
Published in Laboratory medicine
A nontargeted metabolomics approach was established to characterize serum metabolic profile in type 3c diabetes mellitus (T3cDM) secondary to chronic pancreatitis and compare with T2DM. Forty patients were recruited for metabolite analysis based on liquid chromatography-mass spectrometry. Cluster heatmap and KEGG metabolic pathway enrichment analys...
Increasing brain N-acetylneuraminic acid alleviates hydrocephalus-induced neurological deficits.
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Published in CNS neuroscience & therapeutics
This metabolomic study aimed to evaluate the role of N-acetylneuraminic acid (Neu5Ac) in the neurological deficits of normal pressure hydrocephalus (NPH) and its potential therapeutic effect. We analyzed the metabolic profiles of NPH using cerebrospinal fluid with multivariate and univariate statistical analyses in a set of 42 NPH patients and 38 c...
