Bitzer, Markus Ju, Wenjun Subramanian, Lalita Troost, Jonathan P Tychewicz, Joseph Steck, Becky Wiggins, Roger C Gipson, Debbie S Gadegbeku, Crystal A Brosius, Frank C 3rd
...
Published in
American journal of physiology. Renal physiology
Research on kidney diseases is being transformed by the rapid expansion and innovations in omics technologies. The analysis, integration, and interpretation of big data, however, have been an impediment to the growing interest in applying these technologies to understand kidney function and failure. Targeting this urgent need, the University of Mic...
Zhao, Bingyao Nuli, Rebiya Jiao, Yi Zhang, Bing Wang, Ling Guan, Yaqun
Published in
Frontiers in bioscience (Landmark edition)
Impaired glucose regulation (IGR) represents the prediabetic state and is associated with gut microbiota (GM) dysbiosis and chronic inflammation. Tangning Ziyabitusi Tablet (TZT) is a Chinese Uyghur herbal medicine with preventative and therapeutic effects on diabetes, but its hypoglycemic mechanisms are unclear. Thirty-six male Wistar rats were di...
ramos-lopez;, omar
The combination of multiple omics approaches has emerged as an innovative holistic scope to provide a more comprehensive view of the molecular and physiological events underlying human diseases (including obesity, dyslipidemias, fatty liver, insulin resistance, and inflammation), as well as for elucidating unique and specific metabolic phenotypes. ...
Yang, Chuanli Bai, Xinshu Hu, Tianjiao Xue, Xin Su, Xiaohu Zhang, Xuan Wu, Teng Zhang, Mingxia Shen, Xiaobing Dong, Xiushan
...
Published in
Frontiers in Microbiology
Functional constipation is a common functional gastrointestinal disease. In our previous study, we found that the gut microbiota structure was disordered and the level of phenylalanine (Phe) in serum was decreased in constipated women. We conducted the present study to elucidate the role of Phe in remodeling the composition of gut microbiota and th...
Xu, Xiaoying Yang, Hang Xu, Zhen Li, Xiaoqin Leng, Xiangjun
Published in
Frontiers in Nutrition
This study compared the growth, flesh quality and metabolomics of largemouth bass (Micropterus salmoides) fed trash fish and formula feeds. Trash fish (TF), self-made feed (SF) and commercial feed (CF) were prepared with crude protein levels of 172.2 g/kg, 503.5 g/kg and 504.1 g/kg (666.2 g/kg, 547.3 g/kg and 535.1 g/kg based on dry matter), respec...
fernandes;, jolyn
Omics analyses are commonly used for identifying pathways and genes responsible for physiologic and pathologic processes. Though sex is considered a biological variable in rigorous assessments of pulmonary responses to oxidant exposures, the contribution of the murine strain is largely ignored. This study utilized an unbiased integrated assessment ...
Rodas, Gil Ferrer, Eva Reche, Xavier Sanjuan-Herráez, Juan Daniel McCall, Alan Quintás, Guillermo
Published in
Frontiers in Physiology
Professional athletes undertake a variety of training programs to enhance their physical performance, technical-tactical skills, while protecting their health and well-being. Regular exercise induces widespread changes in the whole body in an extremely complex network of signaling, and evidence indicates that phenotypical sex differences influence ...
liu;, yu he chang
Chronic kidney disease caused by a high-fat diet (HFD)-induced metabolic syndrome has received widespread attention. Lycopene has a wide range of biological activities and can improve a variety of chronic diseases through anti-inflammatory effects. In this study, HFD-fed mice were used as a metabolic syndrome model to evaluate the protective effect...
li;, yuansong
Linalool showed a broad-spectrum antibacterial effect, but few studies have elucidated the antibacterial mechanism of linalool on Pseudomonas fragi (P. fragi) to date. The present study aimed to uncover the antimicrobial activity and potential mechanism of linalool against P. fragi by determining key enzyme activities and metabolites combined with ...
lian;, hongxia
Ruminal acidosis often occurs in production, which greatly affects animal health and production efficiency. Subacute rumen acidosis (SARA) occurs when rumen pH drops rapidly to 5.5–5.8, and acute rumen acidosis (ARA) occurs when rumen pH drops below 5.0, but the molecular regulation mechanism of the rumen epithelium after the rapid decrease in pH i...
