Journal of Experimental Botany
This article comments on: Chen J, Zhu M, Liu R, Zhang M, Lv Y, Liu Y, Xiao X, Yuan J, Cai H . 2020. BIOMASS YIELD 1 regulates Sorghum biomass and grain yield via the shikimate pathway. Journal of Experimental Botany 71 , 5506–5520 .
Frontiers in Physiology
White striping, wooden breast, and spaghetti muscle have become common myopathies in broilers worldwide. Several research reports have indicated that the origin of these lesions is metabolic disorders. These failures in normal metabolism can start very early in life, and suboptimal incubation conditions may trigger some of the key alterations on mu...
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal neurodegenerative disorder for which there is no effective curative treatment available and minimal palliative care. Mutations in the gene encoding the TAR DNA-binding protein 43 (TDP-43) are a well-recognized genetic cause of ALS, and an imbalance in energy homeostasis correlat...
Frontiers in Immunology
Cell therapies such as chimeric-antigen receptor (CAR) T-cells and NK cells are cutting-edge methods for treating cancer and other diseases. There is high interest in optimizing drug treatment regimens to best work together with emerging cell therapies, such as targeting epigenetic enzymes to stimulate recognition of tumor cells by immune cells. He...
Cysteine is a semi-essential amino acid that has been positively associated with growth in children. However, transgenerational effects remain unclear. The aim of this analysis was to assess whether maternal plasma total cysteine (tCys) concentration is associated with various growth indicators in infants living in peri-urban settings in Bhaktapur,...
Bacteria have been an integral part of human life since the ancient times either as cooperative tenants living in and around us or as constant threats to our health and wellbeing. Since prehistoric times we unknowingly used them as tools of fermentation and fought against them with haphazardly discovered natural remedies. Today, after more than 3 c...
Animals : an Open Access Journal from MDPI
Simple Summary Castration of male piglets has traditionally been carried out to control boar taint, but animal welfare concerns about surgical castration has brought this practice under scrutiny. In addition, castration decreases growth performance and increases the environmental impact of pork production, so alternatives to castration are needed t...
Frontiers in Cell and Developmental Biology
BCL-2–related ovarian killer (BOK) is—despite its identification over 20 years ago—an incompletely understood member of the BCL-2 family. BCL-2 family proteins are best known for their critical role in the regulation of mitochondrial outer membrane permeabilization during the intrinsic apoptotic pathway. Based on sequence and structural similaritie...
Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
Purpose There are two signal transduction pathways related to glucose metabolism in C2C12 mouse myoblast cells; one through AMP-activated protein kinase (AMPK), and the other through phosphoinositide 3-kinase (PI3K). Ginger is reported to have hypoglycemic effects. The aim of this study was to determine the exact mechanism of action of ginger in th...
Frontiers in Genetics