Sevoflurane exposure during the neonatal period induces long-term memory impairment but not autism-like behaviors.
Published in Paediatric anaesthesia
Our results confirm previous studies that neonatal sevoflurane exposure causes neurodegeneration and long-term memory impairment in mice. However, sevoflurane did not induce autism-like features. Our study suggests that mice are more vulnerable to long-term memory deficits than autism-like behaviors after exposure to sevoflurane.