Cunha, Ana M. Esteves, Madalena das Neves, Sofia P. Borges, Sónia Guimarães, Marco R. Sousa, Nuno Almeida, Armando Leite-Almeida, Hugo
Published in
Frontiers in Behavioral Neuroscience
In rodents, dexterity is commonly analyzed in preference paradigms in which animals are given the chance to use either the left or the right front paws to manipulate food. However, paw preference and dexterity at population and individual levels are controversial as results are incongruent across paradigms. We have therefore developed a semi-quanti...
Niarchou, Maria Calkins, Monica E Moore, Tyler M Tang, Sunny X McDonald-McGinn, Donna M Zackai, Elaine H Emanuel, Beverly S Gur, Ruben C Gur, Raquel E
Published in
Schizophrenia Bulletin
Objective 22q11.2 Deletion Syndrome (22q11.2DS) is associated with increased risk for schizophrenia in adulthood while Attention Deficit Hyperactivity Disorder (ADHD) is the most prevalent diagnosis in childhood. Inattention symptoms are pronounced in 22q11.2DS and given that attentional impairment is a core feature of schizophrenia, inattention sy...
Hamidovic, Ajna
Published in
Frontiers in Pharmacology
Rapid-acting, non-irritating nasal treatment options for smoking cessation pharmacotherapy are lacking. The halt in development is due, in part, to difficulty in delivering compounds across the blood brain barrier. Recently, in both human and animal models, insulin was shown to be capable of being transported to the cerebrospinal fluid and various ...
Chamberlain, S Redden, S Leppink, E Grant, JE
Objective: Gambling is a commonplace phenomenon, existing along a continuum from occasional gambling, to functionally impairing gambling disorder. The Internet may act as a conduit for some gambling behaviors. The impact of problematic Internet use on clinical and cognitive features relevant to gambling has received very little research attention. ...
Voon, V
Background: Impulsivity and reward expectancy are commonly inter-related. Waiting impulsivity, measured using the rodent 5-Choice Serial Reaction Time (5-CSRT) task, predicts compulsive cocaine seeking and sign (or cue) tracking. Here we assess human waiting impulsivity using a novel translational task, the 4-CSRT, and the relationship with reward ...
Caravaggio, Fernando Plitman, Eric Chung, Jun Ku Gerretsen, Philip Kim, Julia Iwata, Yusuke Chakravarty, Mallar Remington, Gary Graff-Guerrero, Ariel
Published in
The European journal of neuroscience
Impulsivity is considered a vulnerability trait for addiction. Recently, we found trait non-planning impulsiveness measured with the Karolinska Scales of Personality was negatively correlated with dopamine D2/3 receptor availability in the ventral striatum of healthy humans. While also observed in rodents, human studies have failed to find this ass...
Weckler, Hanna Kong, Grace Larsen, Helle Cousijn, Janna Wiers, Reinout W Krishnan-Sarin, Suchitra
Published in
Experimental and clinical psychopharmacology
Impulsivity is associated with smoking, difficulties quitting smoking, and approach tendencies toward cigarette stimuli among adolescents. We examined the effects of impulsivity on (a) the association between approach tendencies and adolescents' smoking status and (b) the effectiveness of Cognitive Bias Modification (CBM), a smoking cessation inter...
Geisner, I. M. Koopmann, J. Bamberger, P. Wang, M. Larimer, M. E. Nahum-Shani, I. Bacharach, S.
Published in
Addictive behaviors
BACKGROUND The transition from college to work is both an exciting and potentially high risk time for young adults. As students transition from academic settings to full-time employment, they must navigate new social demands, work demands, and adjust their drinking behaviors accordingly. Research has shown that there are both protective factors and...
Wanmaker, Sabine Leijdesdorff, Sophie Maaike Jorinde Geraerts, Elke van de Wetering, Ben J M Renkema, Peter J Franken, Ingmar H A
Published in
Journal of clinical and experimental neuropsychology
Overall, we did not find evidence for the efficacy of WM training on WMC or clinical symptoms as compared to a placebo training in a population of substance use disorder patients. Future research needs to investigate further whether WMC is an important factor that is associated with substance-abuse-related behavior, and whether working memory train...
Sousa, Sónia S. Sampaio, Adriana Marques, Paulo Gonçalves, Óscar F. Crego, Alberto
Published in
Frontiers in Psychology
Binge drinking (BD) is defined as a pattern of high alcohol intake in a short time followed by periods of abstinence. This behavior is very common in adolescence, a developmental stage characterized by the maturation of the prefrontal and striatal networks, important circuits underlying the capacity to control and regulate the behavior. In this stu...
