Published in Future Medicinal Chemistry
Although the enzyme PARP14 has been associated with negative outcomes in cancers and allergic airway diseases, it may in fact aid in equipping the immune response against the novel 2019 coronavirus.
Published in Journal of Inflammation Research
Background Janus kinases (JAKs) are a family of non-receptor tyrosine kinases involved in multiple malignancies. However, clinical values of JAKs as prognostic markers and potential mechanism as molecular targets in breast invasive carcinoma (BC) are not completely clarified. Methodology TIMER, UALCAN and GEPIA were used to assess the expression an...
Published in Nutrition (Burbank, Los Angeles County, Calif.)
Aim The purpose of this study is determination of interest in vitamins use in COVID-19 pandemic usıng google trends data. Method Searches were made between 1 January 2016 to 30 Agust 2020. First, the word "vitamin" was searched. In addition, the search words "vitamin", " COVID-19", "immunity" and Vitamin D", "Vitamin C", "Vitamin E", "Vitamin A" we...
Although nectar is consumed, primarily as a supplemental food, by a broad range of insects spanning at least five orders, it is processed and stored by only a small number of species, most of which are bees and wasps in the superfamily Apoidea. Within this group, Apis mellifera has evolved remarkable adaptations facilitating nectar processing and s...
Published in International journal of environmental research and public health
The main purpose of this systematic review and meta-analysis was to compare the effects of strength training (ST) and plyometric training (PT) on vertical jump, linear sprint and change of direction (COD) performance in female soccer players. A systematic search of the PubMed, Web of Science, Google Scholar and SportDiscus databases revealed 12 stu...
Published in Oncoimmunology
Drug-induced ferroptosis, an iron-dependent regulatory necrosis, has been proposed for the therapy of pancreatic ductal adenocarcinoma. However, genetically engineered mouse models have revealed that high-iron diets or deletion of pancreatic GPX4 (a key repressor of ferroptosis) accelerate the development of mutant Kras -driven PDAC by activating t...
Published in Journal of Biosciences
In host–parasite co-evolution, parasites are assumed to have an advantage owing to their shorter generation time. Evolution of pathogens within the lifetime of a host individual is implicated as a strong selective force in the evolution of sex and aging in the host. However, this assumption or its testable predictions have not been examined empiric...
Published in Experimental and therapeutic medicine
For a long period, cancer has been believed to be a gene disease, in which oncogenic and suppressor mutations accumulate gradually, finally leading to the malignant transformation of cells. This vision has changed in the last few years, the involvement of the tumor microenvironment, the non-malignant part of the tumors, as an important contributor ...
Published in Gut Microbes
Preterm infants are at risk of multiple morbidities including necrotizing enterocolitis (NEC). Suspected NEC patients receive intravenous antibiotics (AB) to prevent sepsis, although enteral AB is arguably more effective at reducing NEC but is rarely used due to the risk of AB resistance. Fecal microbiota transplantation (FMT) has shown protective ...
Published in Frontiers in Genetics
Genetic selection of disease resistant fish is a major strategy to improve health, welfare and sustainability in aquaculture. Mapping of single nucleotide polymorphisms (SNP) in the fish genome may be a fruitful tool to define relevant quantitative trait loci (QTL) and we here show its use for characterization of Vibrio anguillarum resistant rainbo...
