The lithium-pilocarpine model of epilepsy in rat has been used extensively to investigate basic mechanisms of epilepsy and mimics human temporal lobe epilepsy. Our aim was to investigate longitudinal alterations in metabolism after lithium-pilocarpine induced status epilepticus (SE) using [F-18]FDG microPET. Twenty-eight Wistar rats received lithiu...
Published in Journal of neuroscience research
Although it has been long recognized that the relative balance of pro- and antiapoptotic Bcl-2 proteins is critical in determining the susceptibility to apoptotic death, only a few studies have examined the level of these proteins specifically at mitochondria during postnatal brain development. In this study, we examined the age-dependent regulatio...
Published in Acta crystallographica. Section E, Structure reports online
The male, larva and puparium of Philornis fasciventris (Wulp) are described for the first time, as well as the larval habit and host association. The material was collected in Yucatan, Mexico in a nest of the turquoise-browed motmot, Eumomota superciliosa (Sandbach) (Coraciformes: Momotidae), first host record for this species. E. superciliosa is a...
Published in European Archives of Paediatric Dentistry
Background: Exposure of the pulp by caries is often accompanied by chronic inflammation in the immediate area of the carious lesion and localized abscess formation. Direct pulp capping and vital pulpotomy are two accepted clinical modalities to preserve tooth vitality in cases of pulp exposure in carious young permanent teeth but the success rates ...
Published in Epilepsy research
The results indicate that the developing brain has distinct mechanisms of seizure induced reorganization as compared to the adult brain. Our experiments show that the concept of "resistance of the immature brain to excitotoxicity" is considerably more complicated than generally believed. Morphological plasticity in the immature brain appears more e...
Thirty immatures of Anopheles darlingi Root, Anopheles argyritarsis Robineau-Desvoidy and Anopheles rondoni (Neiva & Pinto) (were found in an artificial lagoon situated near Pardo River, in Ribeirão Preto City, State of São Paulo, Brazil. The presence of immatures of Anopheles darlingi breeding in a lagoon is suggestive of the potential capacity of...
Published in Journal of neurotrauma
Traumatic brain injury (TBI) is a major cause of disability in the pediatric population and can result in abnormal development. Experimental studies conducted in animals have revealed impaired plasticity following developmental TBI, even in the absence of significant anatomical damage. The N-methyl-D-aspartate receptor (NMDAR) is clearly involved i...
Febrile seizures (FSs) typically occur at the onset of fever and do not recur within the same febrile episode despite enduring or increased hyperthermia. Recurrent seizures during the same febrile episode are considered "complex," with potentially altered prognosis. A characterized immature rat model of FS was used to test the hypotheses that (1) a...
Published in Journal of Molecular Neuroscience
Febrile seizures (FSs) typically occur at the onset of fever and do not recur within the same febrile episode despite enduring or increased hyperthermia. Recurrent seizures during the same febrile episode are considered “complex,” with potentially altered prognosis. A characterized immature rat model of FS was used to test the hypotheses that (1) a...
