Stewart, Lewis Ford, Amy Sangal, Vartul Jeukens, Julie Boyle, Brian Kukavica-Ibrulj, Iréna Caim, Shabhonam Crossman, Lisa Hoskisson, Paul A Levesque, Roger
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Published in
Pathogens and disease
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen particularly associated with the inherited disease cystic fibrosis (CF). Pseudomonas aeruginosa is well known to have a large and adaptable genome that enables it to colonise a wide range of ecological niches. Here, we have used a comparative genomics approach to identify changes that...
Kellner, Ronny Bhattacharyya, Amitava Poppe, Stephan Hsu, Tiffany Y Brem, Rachel B Stukenbrock, Eva H
Published in
Genome biology and evolution
Host specialization by pathogens requires a repertoire of virulence factors as well as fine-tuned regulation of gene expression. The fungal wheat pathogen Zymoseptoria tritici (synonym Mycosphaerella graminicola) is a powerful model system for the discovery of genetic elements that underlie virulence and host specialization. We transcriptionally pr...
Kellner, Ronny Bhattacharyya, Amitava Poppe, Stephan Hsu, Tiffany Y Brem, Rachel B Stukenbrock, Eva H
Host specialization by pathogens requires a repertoire of virulence factors as well as fine-tuned regulation of gene expression. The fungal wheat pathogen Zymoseptoria tritici (synonym Mycosphaerella graminicola) is a powerful model system for the discovery of genetic elements that underlie virulence and host specialization. We transcriptionally pr...
Weyrich, Laura S Feaga, Heather A Park, Jihye Muse, Sarah J Safi, Chetan Y Rolin, Olivier Y Young, Sarah E Harvill, Eric T
Published in
The Journal of infectious diseases
Before contacting host tissues, invading pathogens directly or indirectly interact with host microbiota, but the effects of such interactions on the initial stages of infection are poorly understood. Bordetella pertussis is highly infectious among humans but requires large doses to colonize rodents, unlike a closely related zoonotic pathogen, Borde...
Van Buyten, Evelien Banaay, CGB Vera Cruz, C Höfte, Monica
The cultivation of aerobic rice in the tropics enables farmers to save water without lowering productivity. Unfortunately, this system suffers from declining yields due to a disease complex involving nematodes, pathogenic Pythium spp. and nutrient deficiencies. Assessing the impact of each underlying factor can contribute to efficient disease contr...
Malagnini, Valeria Navajas, Maria Migeon, Alain Duso, Carlo
Published in
Experimental and Applied Acarology
Eotetranychus carpini (Oudemans) is an important pest of grapevine (Vitis vinifera L.) in southern Europe. This mite is also found on a number of different plants, including Carpinus betulus L., which commonly occurs in stands and hedgerows bordering vineyards, where it may serve as a potential mite reservoir. The economic importance of this pest h...
Brady, Michael John Radhakrishnan, Padhma Liu, Hui Magoun, Loranne Murphy, Kenan C. Mukherjee, Jean Donohue-Rolfe, Arthur Tzipori, Saul Leong, John M.
Published in
Frontiers in Microbiology
Upon intestinal colonization, enterohemorrhagic Escherichia coli (EHEC) induces epithelial cells to generate actin “pedestals” beneath bound bacteria, lesions that promote colonization. To induce pedestals, EHEC utilizes a type III secretion system to translocate into the mammalian cell bacterial effectors such as translocated intimin receptor (Tir...
Mhedbi, Nadia
La spécificité d'hôte est le résultat de plusieurs phases d'interaction avec l'hôte : attraction, multiplication, colonisation et transmission. Nous avons émis l'hypothèse que la spécificité d'hôte se dessine dès les étapes précoces d'attraction et d'adhésion. Pour tester cette hypothèse, nous avons sélectionné les gènes codant des senseurs du chim...
Walker, Anne Sophie Bouguennec, Annaig Confais, Johann Morgant, Guillaume Leroux, Pierre
Lowder, Bethan V Guinane, Caitriona M Ben Zakour, Nouri L Weinert, Lucy A Conway-Morris, Andrew Cartwright, Robyn A Simpson, A John Rambaut, Andrew Nübel, Ulrich Fitzgerald, J Ross
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Published in
Proceedings of the National Academy of Sciences of the United States of America
The impact of globalization on the emergence and spread of pathogens is an important veterinary and public health issue. Staphylococcus aureus is a notorious human pathogen associated with serious nosocomial and community-acquired infections. In addition, S. aureus is a major cause of animal diseases including skeletal infections of poultry, which ...
