Sampson, P Meyer, K
Published in
Proceedings of the National Academy of Sciences of the United States of America
Treatment of keratosulfates with alkali leads to the formation of 3,6-anhydroglucosaminyl groups in high yield. A similar reaction takes place with heparin and heparitin sulfate, though to a lesser extent. The anhydrosugar was isolated and compared with synthetic 3,6-anhydroglucosamine. The isolated compounds were identical in ion exchange chromato...
Winsten, J A Huang, P C
Published in
Proceedings of the National Academy of Sciences of the United States of America
A protein-DNA transcription complex, isolated from logarithmic-phase cells of Bacillus subtilis, is active in the initiation of new rounds of RNA synthesis in vitro. Transcription directed by the endogenous DNA of the complex is sensitive to inhibitors of initiation. In addition, the effect of addition of a competing template indicates that RNA pol...
Tamm, I
Published in
Proceedings of the National Academy of Sciences of the United States of America
RNA synthesis in isolated HeLa cell nuclei prepared from cells pretreated with 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) is inhibited in a time-dependent manner. After 40-min pretreatment of cells with 60 muM DRB in the presence of actinomycin D (0.04 mug/ml), the rate of RNA synthesis in isolated nuclei, measured by [(3)H]UTP incorpor...
Maffei, Francisco Humberto de Abreu Pinto, A. M. Fabris, Viciany Erique Lastória, S. Rollo, H. D.
Thrombosis was induced in the jugular vein of guinea pigs by damage of the epithelium with a sclerosing solution. The effect of heparin, Dextran 70, acetylsalicylic acid, dipyridamole and phenylbutazone in preventing the development of the thrombus was investigated. Only heparin in high doses showed this effect.
Maffei, Francisco Humberto de Abreu Pinto, A. M. Fabris, Viciany Erique Lastória, S. Rollo, H. D.
Thrombosis was induced in the jugular vein of guinea pigs by damage of the epithelium with a sclerosing solution. The effect of heparin, Dextran 70, acetylsalicylic acid, dipyridamole and phenylbutazone in preventing the development of the thrombus was investigated. Only heparin in high doses showed this effect.
Maffei, Francisco Humberto de Abreu Pinto, A. M. Fabris, Viciany Erique Lastória, S. Rollo, H. D.
Thrombosis was induced in the jugular vein of guinea pigs by damage of the epithelium with a sclerosing solution. The effect of heparin, Dextran 70, acetylsalicylic acid, dipyridamole and phenylbutazone in preventing the development of the thrombus was investigated. Only heparin in high doses showed this effect.
Maffei, Francisco Humberto de Abreu Pinto, A. M. Fabris, Viciany Erique Lastória, S. Rollo, H. D.
Thrombosis was induced in the jugular vein of guinea pigs by damage of the epithelium with a sclerosing solution. The effect of heparin, Dextran 70, acetylsalicylic acid, dipyridamole and phenylbutazone in preventing the development of the thrombus was investigated. Only heparin in high doses showed this effect.
Cappelletti, Renzo Del Rosso, Mario Chiarugi, Vincenzo P.
Published in
Analytical Biochemistry
A new rapid, sensitive, and reproducible method is presented which allows the separation of all known animal glycosaminoglycans (including two subclasses of heparan sulfate, chondroitin 4-sulfate, chondroitin 6-sulfate, dermatan sulfate, hyaluronic acid, heparin, and keratan sulfate) in a single monodimensional electrophoresis on cellulose acetate....
dos Santos, E. Rothschild, Hanna A. Rocha e Silva, M.
The activation of pre-kininogenin to kininogenin (pre-kallikrein to kallikrein) is one of the steps in the series of reactions of a complex system, linked also to fibrinolysis and coagulation, that leads to kinin release in plasma (See Cochrane et al., 1976; Wuepper, 1976; Kaplan et al., 1976; Kaplan et al., 1976). For human plasma, a test using ka...
dos Santos, E. Rothschild, Hanna A. Rocha e Silva, M.
The activation of pre-kininogenin to kininogenin (pre-kallikrein to kallikrein) is one of the steps in the series of reactions of a complex system, linked also to fibrinolysis and coagulation, that leads to kinin release in plasma (See Cochrane et al., 1976; Wuepper, 1976; Kaplan et al., 1976; Kaplan et al., 1976). For human plasma, a test using ka...
