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Rochon, Antoine G Bélisle, Sylvain Couture, Pierre Fortier, Annik Lebon, Jean-Sébastien Deschamps, Alain
Published in
Journal of cardiothoracic and vascular anesthesia
In vivo protamine titration (IVPT) is based on the observation of a plateau on the decay curve of the celite activated clotting times (ACTs) during protamine infusion for heparin reversal. The aim of the present study was to determine the optimal protamine/heparin ratio to reverse anticoagulation using IVPT curves. Prospective, randomized study. Te...
Ranasinghe, Tamra Mays, Traci Quedado, Jeff Adcock, Amelia
Published in
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Administering intravenous IV tissue plasminogen activator (tPA) is the recommended standard of care in acute ischemic stroke (AIS), although it is not recommended to administer intravenous thrombolysis with tPA following heparin reversal with protamine sulfate in patients with AIS. We describe a case series of three patients and the most comprehens...
