Katsimardou, Alexandra Theofilis, Panagiotis Vordoni, Aikaterini Doumas, Michael Kalaitzidis, Rigas G
Published in
International journal of molecular sciences
Beyond their established hypoglycemic, cardioprotective, and nephroprotective properties, sodium-glucose cotransporters 2 (SGLT2) inhibitors exert other pleiotropic actions on blood pressure levels, body weight, and lipid metabolism. Blood pressure (BP) reduction varies based on the background history, including an effect on systolic, diastolic BP,...
njeim, ryan sreeram pannala, sai shanmukha zaidan, nadim habib, toni rajamanuri, medha moussa, elie deeb, liliane el-sayegh, suzanne
Background: Patients with autoimmune diseases experience a higher burden of metabolic syndrome (MetS) and cardiovascular disease (CVD). There is a paucity of data regarding MetS in patients with inflammatory bowel disease (IBD) and its impact on CVD. In this retrospective study, we aimed to evaluate the prevalence of MetS components in IBD patients...
Macrì, Roberta Mollace, Rocco Serra, Maria Scarano, Federica Ritorto, Giovanna Ussia, Sara Cardamone, Antonio Coppoletta, Anna Rita Carresi, Cristina Gliozzi, Micaela
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Published in
International journal of molecular sciences
Heart failure (HF) is a complex condition that affects 1-2% of the global population. The presence of comorbidities like diabetes, hypertension, hyperlipidemia, or obesity has been shown in various studies to elevate mortality and hospitalization rates in HF patients. Insufficient outcomes persist in HF, necessitating additional research to address...
fröhling, tobias semo, dilvin mirna, moritz paar, vera shomanova, zornitsa motloch, lukas j. rukosujew, andreas sindermann, jürgen r. lichtenauer, michael pistulli, rudin
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Background/Objectives: Heart failure (HF) remains a major therapeutic and diagnostic challenge nowadays. Albeit, acute decompensated HF is associated with several clinical signs such as dyspnea or edema, it remains a challenge to use easy accessible and suitable tools, such as biomarkers, to distinguish between patients at risk for an acute decompe...
santini, luca adamo, francesco mahfouz, karim colaiaco, carlo finamora, ilaria de lucia, carmine danisi, nicola gentile, stefania sorrentino, claudia romano, maria grazia
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Background: Heart failure (HF) is a chronic disease with a steadily increasing prevalence, high mortality, and social and economic costs. Furthermore, every hospitalization for acute HF is associated with worsening prognosis and reduced life expectancy. In order to prevent hospitalizations, it would be useful to have instruments that can predict th...
Seron, Pamela Gómez-Pérez, Daniela Opazo-Díaz, Edgardo Oliveros, Maria Jose Contreras, Maria Francisca Salinas, Alejandra Andrade-Mayorga, Omar Marzuca-Nassr, Gabriel Nasri Saavedra, Kathleen Espejo, Cinthya
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Published in
Frontiers in Cardiovascular Medicine
Introduction Comprehensive, hybrid cardiac rehabilitation (CR) models have been scantly investigated in heart failure (HF) populations, particularly in low-resource settings. CO-CREATION-HF aims to evaluate the effectiveness of such a model compared to supervised exercise alone.Methods and analysis A 2 parallel-arm, multi-center randomized clinical...
Falconi, Sirin Okimi, Abiodun Wesley, Shaun Sethi, Pooja Datta, Palika Krutsch, Kaytlin
Published in
Frontiers in Public Health
Han, Quancheng Shi, Jingle Yu, Yiding Yuan, Huajing Guo, Yonghong Liu, Xiujuan Xue, Yitao Li, Yan
Published in
Frontiers in Pharmacology
paraskevaidis, ioannis kourek, christos farmakis, dimitrios tsougos, elias
Heart failure is a complex syndrome and our understanding and therapeutic approach relies mostly on its phenotypic presentation. Notably, the heart is characterized as the most energy-consuming organ, being both a producer and consumer, in order to satisfy multiple cardiac functions: ion exchange, electromechanical coordination, excitation–contract...
Judge, Parminder K Tuttle, Katherine R Staplin, Natalie Hauske, Sibylle J Zhu, Doreen Sardell, Rebecca Cronin, Lisa Green, Jennifer B Agrawal, Nikita Arimoto, Ryoki
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Published in
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
Patients with chronic kidney disease (CKD) are at risk of progressive loss of kidney function, heart failure, and cardiovascular death despite current proven therapies, including renin-angiotensin system inhibitors (RASi), sodium glucose co-transporter-2 inhibitors (SGLT2i), and statin-based regimens. RASi and SGLT2i reduce risk of CKD progression ...
