Wu, Yung-Fu Sytwu, Huey-Kang Lung, For-Wey
Published in
Frontiers in Psychiatry
Background In psychiatric illness, pathogenic role of neuroinflammation has been supported by multiple lines of evidence. Astrocytes contribute to the blood-brain barrier (BBB) with formation of the “glymphatic” drainage system of the central nervous system (CNS) through perivascular processes. Found primarily at the end-feet of astrocytes, the aqu...
Gao, Meng Zeng, Kuo Li, Ya Liu, Yong-ping Xia, Xi Xu, Feng-ling Yao, Jun Wang, Bao-jie
Published in
The Journal of International Medical Research
Objective Schizophrenia is a severe neurodevelopmental disorder with a complex genetic and environmental etiology. The gene encoding EF-hand domain-containing protein D2 ( EFHD2 ) may be a genetic risk locus for schizophrenia. Methods We genotyped four EFHD2 single-nucleotide polymorphisms (281 schizophrenia cases [SCZ], 321 controls) from northern...
Djaoud, Zakia Parham, Peter
In all human cells, human leukocyte antigen (HLA) class I glycoproteins assemble with a peptide and take it to the cell surface for surveillance by lymphocytes. These include natural killer (NK) cells and γδ T cells of innate immunity and αβ T cells of adaptive immunity. In healthy cells, the presented peptides derive from human proteins, to which ...
Hernandez, Javier Meints, Brigid Hayes, Patrick
Published in
Frontiers in plant science
Changing production scenarios resulting from unstable climatic conditions are challenging crop improvement efforts. A deeper and more practical understanding of plant genetic resources is necessary if these assets are to be used effectively in developing improved varieties. In general, current varieties and potential varieties have a narrow genetic...
Aliloo, Hassan Mrode, Raphael Okeyo, A. M. Gibson, John P.
Published in
Frontiers in Genetics
Understanding the genetic structure of adaptation and productivity in challenging environments is necessary for designing breeding programs that suit such conditions. Crossbred dairy cattle in East Africa resulting from over 60 years of crossing exotic dairy breeds with indigenous cattle plus inter se matings form a highly variable admixed populati...
Yang, Yunzhou Zan, Yanjun Honaker, Christa F. Siegel, Paul B. Carlborg, Örjan
Published in
Genes
Bi-directional selection for increased and decreased 56-day body weights (BW56) has been applied to two lines of White Plymouth Rock chickens—the Virginia high (HWS) and low (LWS) body weight lines. Correlated responses have been observed, including negative effects on traits related to fitness. Here, we use high and low body weight as proxies for ...
Gu, Kunfang Zhang, Yue Sun, Ke Jiang, Xiubo
Published in
Bioscience Reports
A genome-wide association study (GWAS) in Chinese twins was performed to explore associations between genes and pulse pressure (PP) in 2012, and detected a suggestive association in the phosphatase and actin regulator 1 ( PHACTR1 ) gene on chromosome 6p24.1 (rs1223397, P =1.04e−07). The purpose of the present study was to investigate associations o...
Etougbetche, Jonas Houemenou, Gualbert Dossou, Henri-Joël Badou, Sylvestre Gauthier, Philippe Abdou Karim, Issaka Youssao Nicolas, Violaine Dobigny, Gauthier
Black rats (Rattus rattus) are native to the Indian subcontinent but have now colonized most continents and islands following human movements and international trade. They are involved in the circulation and transmission to humans of many zoonotic agents as well as in massive damage to food stocks and native biodiversity in the regions they have se...
Taylor, Chantal L. Barker, Nigel P. Barber-James, Helen M. Villet, Martin H. Pereira-da-Conceicoa, Lyndall L.
Published in
ZooKeys
This study investigates genetic diversity in three species of Ephemeroptera , one eurytopic and therefore widespread ( Afroptilum sudafricanum ) and two stenotopic and thus endemic ( Demoreptus natalensis and Demoreptus capensis ) species, all of which co-occur in the southern Great Escarpment, South Africa. Mitochondrial DNA was analysed to compar...
Wang, Jinhui Wang, Jieqi Ma, Chao Zhou, Ziqi Yang, Decheng Zheng, Junzan Wang, Qi Li, Huiwen Zhou, Hongyang Sun, Zhijun
...
Published in
Frontiers in Plant Science
In some legume–rhizobium symbioses, host specificity is influenced by rhizobial type III effectors-nodulation outer proteins (Nops). However, the genes encoding host proteins that interact with Nops remain unknown. In this study, we aimed to identify candidate soybean genes associated with NopD, one of the type III effectors of Sinorhizobium fredii...
