Aga, Heja Hallahan, Nicole Gottmann, Pascal Jaehnert, Markus Osburg, Sophie Schulze, Gunnar Kamitz, Anne Arends, Danny Brockmann, Gudrun Schallschmidt, Tanja
...
Published in
Frontiers in Genetics
Type 2 diabetes (T2D) is a complex metabolic disease regulated by an interaction of genetic predisposition and environmental factors. To understand the genetic contribution in the development of diabetes, mice varying in their disease susceptibility were crossed with the obese and diabetes-prone New Zealand obese (NZO) mouse. Subsequent whole-genom...
Marshall, Charla Sturk-Andreaggi, Kimberly Ring, Joseph D. Dür, Arne Parson, Walther
Published in
Genes
Given the enhanced discriminatory power of the mitochondrial DNA (mtDNA) genome (mitogenome) over the commonly sequenced control region (CR) portion, the scientific merit of mitogenome sequencing is generally accepted. However, many laboratories remain beholden to CR sequencing due to privacy policies and legal requirements restricting the use of d...
Ocejo-Vinyals, J. Gonzalo Gonzalez-Gay, Miguel A. Fernández-Viña, Marcelo A. Cantos-Mansilla, Juan Vilanova, Iosune Blanco, Ricardo González-López, Marcos A.
Published in
Journal of Clinical Medicine
Hidradenitis suppurativa (HS) is a chronic inflammatory cutaneous disease of the hair follicle typically presenting recurrent, painful, and inflamed lesions on the inverse areas of the body. Although its pathogenesis remains unknown, the immune system appears to play a potential role. To date, two previous studies have not found any association bet...
Davydova, Yu. D. Kazantseva, A. V. Enikeeva, R. F. Mustafin, R. N. Lobaskova, M. M. Malykh, S. B. Gilyazova, I. R. Khusnutdinova, E. K.
Published in
Russian Journal of Genetics
AbstractOxytocin represents one of the key element regulating social activity and aggressive behavior via its binding to oxytocin receptor (OXTR). Considering the multifactorial nature of developing aggression, the present study aimed to assess the main effects of the OXTR (rs53576, rs237911, rs7632287, rs2254298, rs2228485, rs13316193) gene polymo...
Kamaraj, R. Balakrishnan, K. Dhivakar, M. Rathika, C. Albert, C. Justinkumar, P. Navaneethakannan, K.
Published in
Russian Journal of Genetics
AbstractThe present study was aimed to study HLA-DRB1, -DQB1 alleles and haplotypes of two endogamous groups of South India. PCR-SSP typing of HLA-DRB1, -DQB1 alleles were performed on 63 Mukkuvar, primarily a coastal population and 101 Valayar, a population primarily living on the fringes of forest areas. Genetic distances, neighbor-joining dendro...
Revelo, Herman Alberto López-Alvarez, Diana Landi, Vincenzo Rizzo, Lauden Alvarez, Luz Angela
Published in
Animals : an Open Access Journal from MDPI
Simple Summary Creole sheep were introduced in South America by Spanish colonizers by the end of the fifteenth century. However, the exact dynamics of their formation remains uncertain. There is no consensus on the arrival of hair sheep of African origin, which may have reached the Caribbean coasts at different periods, compared to wool sheep that ...
Stone, Chris M Zuo, Zhen Li, Bo Ruiz, Marilyn Swanson, Jack Hunt, Jason Kim, Chang-Hyun Smith, Rebecca L
Published in
Journal of medical entomology
The spread of the Asian tiger mosquito, Aedes albopictus Skuse, throughout the United States has implications for the transmission potential of vector-borne diseases. We used a 30-yr data set of occurrence records in Illinois and developed a hierarchical Bayesian model to shed light on the patterns and processes involved in the introduction and exp...
Shen, Lishuang Dien Bard, Jennifer Biegel, Jaclyn A. Judkins, Alexander R. Gai, Xiaowu
Published in
Frontiers in Microbiology
Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the city-, state-, and country-levels, and temporal transmissions. This points to the effectiveness o...
Yuan, Yiming Yang, Shanshan Deng, Dan Chen, Yulong Zhang, Caixia Zhou, Ruixue Su, Zhiguang
Published in
IUBMB life
Short-chain acyl-CoA dehydrogenase (SCAD), encoded by the Acads gene, functions in the mitochondrial β-oxidation of saturated short-chain fatty acids. SCAD deficiency results in mitochondrial dysfunction, which is one underlying biological mechanism of chronic obstructive pulmonary disease (COPD) pathogenesis. In this case-control study, we aimed t...
Sargazi, Saman Heidari Nia, Milad Sheervalilou, Roghayeh Mirinejad, Shekoufeh Harati-Sadegh, Mahdiyeh Moudi, Mahdiyeh Saravani, Ramin Shakiba, Mansoor
Published in
International Journal of Molecular and Cellular Medicine
Grainyhead-like (GRHL) transcription factors were recently linked to the etiology of neural tube defects (NTDs). Overlapping patterns in the variation of schizophrenia (SCZ) incidence with that of NTDs suggests the presence of common etiological risk factors. This preliminary study was designed to examine the relationship between two missense varia...
