Published in Annual Review of Neuroscience
How the nervous system is wired has been a central question of neuroscience since the inception of the field, and many of the foundational discoveries and conceptual advances have been made through the study of invertebrate experimental organisms, including Caenorhabditis elegans and Drosophila melanogaster. Although many guidance molecules and rec...
Published in Pharmacoepidemiology and drug safety
Because preapproval clinical trials typically exclude pregnant women, the evidence on drug safety during pregnancy required to inform drug labeling must come from postapproval controlled observational studies. Common designs have included pregnancy registries and case-control studies. Recently, pregnancy cohorts nested within healthcare utilization...
Published in Therapeutic Innovation & Regulatory Science
In the advanced medical field, there is a constant need for efficient guidance formulation by regulators. Technology forecasting as a surveillance for regulation needs may be an effective solution by notifying regulatory authorities of the possible future changes in regulations. However, the lack of tangible frameworks has made the relationship bet...
Published in Journal of fish biology
The role of vision and the lateral-line system in fish-screen avoidance behaviours was investigated in shiner surfperch Cymatogaster aggregata and staghorn sculpin Leptocottus armatus. Avoidance experiments were conducted in front of water-diversion-type wedge-wire fish screens in a laboratory flume with a 0.3 m s-1 water velocity. Fish contacted t...
Published in Frontiers in Public Health
Published in Canada Communicable Disease Report
Background Many different influenza vaccines are authorized for use in Canada and new evidence on influenza and vaccines is continually emerging. The National Advisory Committee on Immunization (NACI) provides annual recommendations regarding the use of seasonal influenza vaccines to the Public Health Agency of Canada (PHAC) for the upcoming influe...
Published in Journal of visualized experiments : JoVE
Successful fertilization is fundamental to sexual reproduction, yet little is known about the mechanisms that guide sperm to oocytes within the female reproductive tract. While in vitro studies suggest that sperm of internally fertilizing animals can respond to various cues from their surroundings, the inability to visualize their behavior inside t...
Published in Frontiers in Public Health
Accumulated evidence demonstrates the centrality of social psychology to the behavior of members of the public as immediate responders in emergencies. Such public behavior is a function of social psychological processes—in particular identities and norms . In addition, what the authorities and relevant professional groups assume about the social ps...
Published in Journal of Anatomy
The path taken by the loop of Henle, from renal cortex to medulla and back, is critical to the ability of the kidney to concentrate urine and recover water. Unlike most developing tubules, which navigate as blind‐ended cylinders, the loop of Henle extends as a sharply bent loop, the apex of which leads the double tubes behind it in a ‘V’ shape. Her...
Published in Automation and Remote Control
We propose a method of simplified group target assignment, not only providing the assignment of targets to interceptors but also making it possible to construct expected intercept trajectories taking into account real-world restrictions, elimination of participants, and target priorities.
