Tang, Furong Richardson, Nainoa Albina, Audrey Chaboissier, Marie-Christine Perea-Gomez, Aitana
Published in
Cells
The transcription factors SRY and SOX9 and RSPO1/WNT4/β-Catenin signaling act as antagonistic pathways to drive testis and ovary development respectively, from a common gonadal primordium in mouse embryos. In this work, we took advantage of a double knockout mouse model to study gonadal development when Sox9 and Wnt4 are both mutated. We show that ...
Lerebours, Adelaide Robson, Samuel Sharpe, Colin Nagorskaya, Liubov Gudkov, Dmitri Haynes-Lovatt, Charlotte Smith, Jim
Fish have been highly exposed to radiation in freshwater systems after the Chernobyl Nuclear Power Plant (NPP) accident in 1986 and in freshwater and marine systems after the more recent Fukushima NPP accident in 2011. In the years after the accident, the radioactivity levels rapidly declined due to radioactive decay and environmental processes, bu...
Piprek, Rafal P. Kolasa, Michal Podkowa, Dagmara Kloc, Malgorzata Kubiak, Jacek Z.
Published in
Cells
Normal gonad development assures the fertility of the individual. The properly functioning gonads must contain a sufficient number of the viable germ cells, possess a correct architecture and tissue structure, and assure the proper hormonal regulation. This is achieved by the interplay between the germ cells and different types of somatic cells. N-...
Singh, Shilpi Singh, Shio Kumar
Published in
Journal of applied toxicology : JAT
Perfluoroalkyl acids (PFAAs) are widely used in commercial products and are found in many goods of daily use. Perfluorononanoic acid (PFNA) is one of the PFAAs that possesses endocrine disrupting properties and we have recently shown that PFNA affects testicular functions in Parkes mice. Exposure to environmental endocrine disruptors during fetal l...
Asaduzzaman, Md Rahi Noor, Aysha Rahman, Md Moshiur Akter, Sumi Hoque, Nayeema Ferdausy Shakil, Abrar Wahab, Md Abdul
Published in
Biology
A multidisciplinary approach was applied to explore deeper knowledge about the reproductive biology and ecology of the green mussel ( Perna viridis ) by interlinking among ecological factors, ingested gut plankton, gonad fatty acid profile, and reproductive traits. Mussels were collected throughout the year from the coastal region of the Bay of Ben...
Yan, Yi-Lin Batzel, Peter Titus, Tom Sydes, Jason Desvignes, Thomas BreMiller, Ruth Draper, Bruce Postlethwait, John H
Published in
Genetics
Fetal mammalian testes secrete Anti-Müllerian hormone (Amh), which inhibits female reproductive tract (Müllerian duct) development. Amh also derives from mature mammalian ovarian follicles, which marks oocyte reserve and characterizes polycystic ovarian syndrome. Zebrafish (Danio rerio) lacks Müllerian ducts and the Amh receptor gene amhr2 but, cur...
Tang, Zhanyang Zhou, Yi Xiao, Jun Zhong, Huan Miao, Weiwei Guo, Zhongbao Zhang, Xu Zhou, Lei Luo, Yongju
Published in
Frontiers in Genetics
This study investigated the molecular mechanisms involved in ovarian transcriptomic responses in Nile tilapia under different photoperiod regimes. Histological analysis indicated that ovarian development was significantly affected by photoperiod. The photoperiods tested were as follows: LD (12 h light:12 h dark), LL (24 h light:0 h dark), and DD (0...
Zhang, Hui Kang, Myounghee Wu, Jinming Wang, Chengyou Li, Junyi Du, Hao Yang, Haile Wei, Qiwei
Published in
Animals : an Open Access Journal from MDPI
Simple Summary A river thermal regime is critically influencing the aquatic ecosystem and human-induced water temperature alteration occurs commonly worldwide. In large river systems, thermal alterations do not readily arise because of the huge water volume. The Yangtze River has the third greatest water flow, is the third longest river, and is one...
Bi, Honglun Xu, Xia Li, Xiaowei Zhang, Yong Huang, Yongping Li, Kai Xu, Jun
Published in
Insects
The domesticated silkworm is an economically important insect that is widely used as a lepidopteran insect model. Although somatic sex determination in the silkworm is well characterized, germline sex determination is not. Here, we used the transgenic-based CRISPR/Cas9 genome editing system to study the function of the Ovo gene in Bombyx mori . BmO...
Stévant, Isabelle Kühne, Françoise Greenfield, Andy Chaboissier, Marie-Christine Dermitzakis, Emmanouil T Nef, Serge
Published in
Cell reports
Sex determination is a unique process that allows the study of multipotent progenitors and their acquisition of sex-specific fates during differentiation of the gonad into a testis or an ovary. Using time series single-cell RNA sequencing (scRNA-seq) on ovarian Nr5a1-GFP+ somatic cells during sex determination, we identified a single population of ...