White, beige, and brown adipose tissues play a crucial role in maintaining energy homeostasis. Due to the heterogeneous and diffuse nature of fat pads, this balance requires a fine and coordinated control of many actors and therefore permanent dialogues between these tissues and the central nervous system. For about two decades, many studies have b...
Published in Frontiers in Neuroscience
Leptin plays a critical role in regulating appetite, energy expenditure and body weight, making it a key factor in maintaining a healthy balance. Despite numerous efforts to develop therapeutic interventions targeting leptin signaling, their effectiveness has been limited, underscoring the importance of gaining a better understanding of the mechani...
Published in Critical reviews in food science and nutrition
An imbalance between energy consumption and energy expenditure causes obesity. It is characterized by increased adipose accumulation and accompanied by chronic low-grade inflammation. Many studies have suggested that the gut microbiota of the host mediates the relationship between high-fat diet consumption and the development of obesity. Diet and n...
Published in Frontiers in Agronomy
Determining crop evapotranspiration (ET) is essential for managing water at various scales, from regional water accounting to farm irrigation. Quantification of ET may be carried out by several procedures, being eddy covariance and energy balance the most established methods among the research community. One major limitation is the high cost of the...
Published in Frontiers in Energy Research
Ground source heat pumps (GSHPs) are highly efficient for heating and cooling buildings. Among the different types of ground source heat pumps, horizontal ground heat exchangers (HGHEs) gaining popularity due to their cost-effectiveness, ease of installation and high regeneration capacity. However, studies on the interaction and influence of the lo...
Abstract The N -acyl phosphatidylethanolamine-specific phospholipase D (NAPE-PLD) catalyzes the production of N -acylethanolamines (NAEs), a family of endogenous bioactive lipids, which are involved in various biological processes ranging from neuronal functions to energy homeostasis and feeding behaviors. Reward-dependent behaviors depend on the d...
Published in FASEB journal : official publication of the Federation of American Societies for Experimental Biology
A protein altering variant in the gene encoding zinc finger homeobox-3 (ZFHX3) has recently been associated with lower BMI in a human genome-wide association study. We investigated metabolic parameters in mice harboring a missense mutation in Zfhx3 (Zfhx3Sci/+ ) and looked for altered in situ expression of transcripts that are associated with energ...
Published in Frontiers in Endocrinology
Various models of mitochondrial stress result in induction of the stress-responsive cytokines fibroblast growth factor 21 (FGF21) and growth differentiation factor 15 (GDF15). This is an adaptive mechanism downstream of the mitochondrial integrated stress response frequently associated with improvements in systemic metabolic health. Both FGF21 and ...
Published in Research square
The N-acyl phosphatidylethanolamine-specific phospholipase D (NAPE-PLD) catalyzes the production of N-acylethanolamines (NAEs), a family of endogenous bioactive lipids, which are involved in various biological processes ranging from neuronal functions to energy homeostasis and feeding behaviors. Reward-dependent behaviors depend on dopamine (DA) tr...
Published in Frontiers in Earth Science
In the high altitude Hindukush Karakoram Himalaya (HKH) mountains, the complex weather system, inaccessible terrain and sparse measurements make the elevation-distributed precipitation and temperature among the most significant unknowns. The elevation-distributed snow and glacier dynamics in the HKH region are also little known, leading to serious ...
