Age-dependent accumulation of protein-DNA cross-links in mouse liver.
This thesis concerns the partial purification and properties of an RNA-dependent RNA polymerase (RNA replicase) produced upon infection of Vigna unguiculata plants with Cowpea Mosaic Virus (CPMV). The enzyme is believed to be coded, at least in part, by the virus genome and to be responsible for the replication of the virus RNA.In chapter 1 we desc...
Parasitic diseases cause serious illness and often death in human populations and domestic livestock, particularly in the tropics. These include malaria, trypanosomiasis and tick-borne diseases. Important recent developments in the fields of immunology, biochemistry and molecular biology might make it possible to control some of these diseases. Thi...