Slobodin, Gleb Kessel, Aharon Kofman, Natalie Toubi, Elias Rosner, Itzhak Odeh, Majed
Published in
Inflammation
Decreased levels of class II major histocompatibility complex (MHC) expression and impaired formation of immunological synapse by dendritic cells (DCs) of HLA-B27 transgenic rats have been recently demonstrated. The resulting dysfunction of DCs may be implicated in the pathogenesis of the HLA-B27-related disease in transgenic animals. The phenotype...
Joubert, Pierre-Emmanuel Albert, Matthew L.
Phagocytosis of dying cells constitutes an important mechanism of antigen capture for the cross-priming of CD8(+) T cells. This process has been shown to be critical for achieving tumor and viral immunity. While most studies have focused on the mechanisms inherent in the dendritic cell that account for exogenous antigen accessing MHC I, several rec...
Benson, Heather L Suzuki, Hidemi Lott, Jeremy Fisher, Amanda Jo Walline, Crystal Heidler, Kathleen M Brutkiewicz, Randy Blum, Janice S Wilkes, David S
Published in
Respiratory Research
BackgroundDirect allorecognition, i.e., donor lung-derived dendritic cells (DCs) stimulating recipient-derived T lymphocytes, is believed to be the key mechanism of lung allograft rejection. Myeloid (cDCs) and plasmacytoid (pDCs) are believed to have differential effects on T cell activation. However, the roles of each DC type on T cell activation ...
Marques, Otavio Cabral Arslanian, Christina Ramos, Rodrigo Nalio Morato, Mariana Schimke, LenaFriederike Soeiro, Paulo Vitor Jancar, Sonia Ferreira, Janira Fernandes Weber, Cristina Worm Kuntze, Gisele
...
Web of Science
Chen, Zhuo Yu, Bin Wu, Xian-Lin Dai, Cong-Qi Qian, Guo-Qiang Yu, Jian-Zhong He, Hai-Bin Wang, Zhi-Xin Hou, Jun Chen, Xiao-Yin
...
Published in
Chinese journal of integrative medicine
Two kinds of hepatoma cell line's supernatant can inhibit the immunologic function of DCs. This suppressive effect may be related to the inhibition of NF-κB/Rel pathway. CMP may up-regulate the DCs function by activating the NF-κB/Rel pathway.
Moreno, Ana Carolina Ramos Ferreira, Karen Spadari Ferreira, Lucas Gonçalves Almeida, Sandro Rogério de Martinez, Marina Baquerizo
SciELO
Moreno, Ana Carolina Ramos Ferreira, Karen Spadari Ferreira, Lucas Gonçalves Almeida, Sandro Rogério de Martinez, Marina Baquerizo
The innate and adaptive immune responses of dendritic cells (DCs) to enteroinvasive Escherichia coli (EIEC) infection were compared with DC responses to Shigella flexneri infection. EIEC triggered DCs to produce interleukin (IL)-10, IL-12 and tumour necrosis factor (TNF)-α, whereas S. flexneri induced only the production of TNF-α. Unlike S. flexner...
Liu, Yinping Wu, Yuet Lam, Kwok-Tai Lee, Pamela Pui-Wah Tu, Wenwei Lau, Yu-Lung
Published in
Journal of Clinical Immunology
IntroductionInfluenza virus is a potential cause of severe disease in the immunocompromised. X-linked agammaglobulinemia (XLA) is a primary immunodeficiency characterized by the lack of immunoglobulin, B cells, and plasma cells, secondary to mutation in Bruton’s tyrosine kinase (Btk) gene. Btk is expressed in both B and dendritic cells (DC). Howeve...
Huang, Jinghe Al-Mozaini, Maha Rogich, Jerome Carrington, Mary F Seiss, Katherine Pereyra, Florencia Lichterfeld, Mathias Yu, Xu G
Published in
Retrovirology
BackgroundHIV-1 infection is associated with profound dysfunction of myeloid dendritic cells, for reasons that remain ill-defined. Soluble HLA class I molecules can have important inhibitory effects on T cells and NK cells, but may also contribute to reduced functional properties of professional antigen-presenting cells. Here, we investigated the e...
Hopkins, John Mabbott, Neil Wathne, Gwennaëlle C L J J
United Kingdom
