Modeling the mass transfers during the elaboration of chitosan-activated carbon composites for medical applications
International audience
Tissue response to composite hydrogels for vertical bone augmentation in the rat.
...Published in Journal of biomedical materials research. Part A
The objective of the present study was to develop a preclinical animal model for evaluating bone augmentation and to examine the level of bone augmentation induced by hydrogel composites. Design criteria outlined for the development of the animal model included rigid immobilization of bilateral implants apposed to the parietal bone of the rat, whil...
Recent Advances in the Synthesis and Biomedical Applications of Nanocomposite Hydrogels.
Published in Pharmaceutics
Hydrogels sensitive to electric current are usually made of polyelectrolytes and undergo erosion, swelling, de-swelling or bending in the presence of an applied electric field. The electrical conductivity of many polymeric materials used for the fabrication of biomedical devices is not high enough to achieve an effective modulation of the functiona...
Physical and mechanical properties of thermosensitive xanthan/collagen-inspired protein composite hydrogels
Functionalization of xanthan hydrogels is of interest for biomaterial applications. The authors report characterization of electrostatic complexation of xanthan with a recombinant collagen-inspired triblock protein polymer. This polymer has one charged polylysine end-block that can bind to xanthan by electrostatic interactions, and another end-bloc...
Chitosan-based composite hydrogels for biomedical applications
Published in Macromolecular Research
During the last decade, hydrogels prepared from biodegradable polymers, especially natural biodegradable polymers, have been studied extensively for drug delivery and tissue engineering. Chitosan, one of the most abundant natural polymers, is a good candidate and the most widely studied polymer for biomedical applications. To improve physiochemical...
Green synthesis of tea Ag nanocomposite hydrogels via mint leaf extraction for effective antibacterial activity.
Published in Journal of biomaterials science. Polymer edition
In this report, we investigated the swelling behavior and antibacterial property of nanosilver composite hydrogels made from tea with polyacrylamide via a free-radical polymerization and green process technique. This is probably for the first time; tea-based nano silver composite hydrogels were developed. The composite hydrogels comprise embedded n...
Dual-pH/Magnetic-Field-Controlled Drug Delivery Systems Based on Fe3 O4 @SiO2 -Incorporated Salecan Graft Copolymer Comp...
Published in ChemMedChem
Salecan is a water-soluble extracellular β-glucan and has excellent physicochemical and biological properties for hydrogel preparation. In this study, a new pH/magnetic field dual-responsive hydrogel was prepared by the graft copolymerization of salecan with 4-pentenoic acid (PA) and N-hydroxyethylacrylamide (HEAA) in the presence of Fe3 O4 @SiO2 n...
3D Printing and Electrospinning of Composite Hydrogels for Cartilage and Bone Tissue Engineering
Published in Polymers
Injuries of bone and cartilage constitute important health issues costing the National Health Service billions of pounds annually, in the UK only. Moreover, these damages can become cause of disability and loss of function for the patients with associated social costs and diminished quality of life. The biomechanical properties of these two tissues...
Low-Cost Advanced Hydrogels of Calcium Alginate/Carbon Nanofibers with Enhanced Water Diffusion and Compression Properti...
Published in Polymers
A series of alginate films was synthesised with several calcium chloride cross-linker contents (from 3 to 18% w/w ) with and without a very low amount (0.1% w/w ) of carbon nanofibers (CNFs) in order to reduce the production costs as much as possible. The results of this study showed a very significant enhancement of liquid water diffusion and mech...
A Cellulose/Laponite Interpenetrated Polymer Network (IPN) Hydrogel: Controllable Double-Network Structure with High Mod...
Published in Polymers
Laponite XLS™, which is a synthetic clay of nanometric dimensions containing a peptizing agent, has been associated with silanized hydroxypropylmethylcellulose (Si-HPMC) to form, after crosslinking, a novel composite hydrogel. Different protocols of sample preparation were used, leading to different morphologies. A key result was that the storage m...
