A multimeric carcinoembryonic antigen signal inhibits the activation of human T cells by a SHP-independent mechanism: a ...
Published in International journal of cancer. Journal international du cancer
Carcinoembryonic antigen (CEA) is a well-known tumor antigen that is found in the serum of patients with various cancers and is correlated with an increased risk of cancer recurrence and metastasis. To understand the tumor environment and to develop antitumor therapies, CEA has been studied as an antigen to activate/tolerate specific T cells. In th...