Kocgozlu, Leyla Saw, Thuan Beng Le, Anh Phuong Yow, Ivan Shagirov, Murat Wong, Eunice Mège, René-Marc Lim, Chwee Teck Toyama, Yusuke Ladoux, Benoit
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Published in
Current biology : CB
The control of tissue growth, which is a key to maintain the protective barrier function of the epithelium, depends on the balance between cell division and cell extrusion rates [1, 2]. Cells within confluent epithelial layers undergo cell extrusion, which relies on cell-cell interactions [3] and actomyosin contractility [4, 5]. Although it has bee...
Delgado-Ruíz, Rafael Arcesio Gomez Moreno, Gerardo Aguilar-Salvatierra, Antonio Markovic, Aleksa Mate-Sánchez, Jose Eduardo Calvo-Guirado, José Luis
Published in
Clinical oral implants research
Within the limitations of this experimental study, it may be concluded that (i) Roughness is increased and chemical composition enhanced on the surface of zirconia implants with microgrooves. (ii) The LSA of microgrooved zirconia implants is greater and provides more available surface compared with implants of the same dimensions without microgroov...
Ye, Kai Cao, Luping Li, Shiyu Yu, Lin Ding, Jiandong
Published in
ACS applied materials & interfaces
Stem cells are capable of sensing and responding to the mechanical properties of extracellular matrixes (ECMs). It is well-known that, while osteogenesis is promoted on the stiff matrixes, adipogenesis is enhanced on the soft ones. Herein, we report an "abnormal" tendency of matrix-stiffness-directed stem cell differentiation. Well-defined nanoarra...
Ye, Kai Cao, Luping Li, Shiyu Yu, Lin Ding, Jiandong
Published in
ACS applied materials & interfaces
Stem cells are capable of sensing and responding to the mechanical properties of extracellular matrixes (ECMs). It is well-known that, while osteogenesis is promoted on the stiff matrixes, adipogenesis is enhanced on the soft ones. Herein, we report an "abnormal" tendency of matrix-stiffness-directed stem cell differentiation. Well-defined nanoarra...
Galgoczi, Erika Jeney, Florence Gazdag, Annamaria Erdei, Annamaria Katko, Monika Nagy, Domonkos M Ujhelyi, Bernadett Steiber, Zita Gyory, Ferenc Berta, Eszter
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Published in
The Journal of endocrinology
During the course of Graves' orbitopathy (GO), orbital fibroblasts are exposed to factors that lead to proliferation and extracellular matrix (ECM) overproduction. Increased levels of tissue plasminogen activator inhibitor type 1 (PAI-1 (SERPINE1)) might promote the accumulation of ECM components. PAI-1 expression is regulated by cell density and v...
Galgoczi, Erika Jeney, Florence Gazdag, Annamaria Erdei, Annamaria Katko, Monika Nagy, Domonkos M Ujhelyi, Bernadett Steiber, Zita Gyory, Ferenc Berta, Eszter
...
Published in
The Journal of endocrinology
During the course of Graves' orbitopathy (GO), orbital fibroblasts are exposed to factors that lead to proliferation and extracellular matrix (ECM) overproduction. Increased levels of tissue plasminogen activator inhibitor type 1 (PAI-1 (SERPINE1)) might promote the accumulation of ECM components. PAI-1 expression is regulated by cell density and v...
Yanagida, Kosuke Sakuda, Ayako Suzuki-Minakuchi, Chiho Shintani, Masaki Matsui, Kazuhiro Okada, Kazunori Nojiri, Hideaki
Published in
Bioscience, biotechnology, and biochemistry
The transferability of plasmids pCAR1, pB10, R388, and NAH7 was compared using the same donor-recipient system at different cell density combinations in liquid or on a solid surface. pCAR1 was efficiently transferred in liquid, whereas the other plasmids were preferentially transferred on a solid surface. Difference of liquid or solid affected the ...
Wagstaff, Laura Goschorska, Maja Kozyrska, Kasia Duclos, Guillaume Kucinski, Iwo Chessel, Anatole Hampton-O’Neil, Lea Bradshaw, Charles Allen, George E Rawlins, Emma
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Cell competition is a quality control mechanism that eliminates unfit cells. How cells compete is poorly understood, but it is generally accepted that molecular exchange between cells signals elimination of unfit cells. Here we report an orthogonal mechanism of cell competition, whereby cells compete through mechanical insults. We show that MDCK ce...
Klemp, Marisa Meinke, Martina C Weinigel, Martin Röwert-Huber, Hans-Joachim König, Karsten Ulrich, Martina Lademann, Juergen Darvin, Maxim E
Published in
Experimental dermatology
The routine diagnostic procedure of actinic keratosis (AK) and invasive squamous cell carcinoma (SCC) is a histological examination after taking a biopsy. In the past decades, non-invasive optical methods for skin examination have been developed. Patients with clinical diagnosis of AK or SCC were examined. The morphological criteria were determined...
Klemp, Marisa Meinke, Martina C Weinigel, Martin Röwert-Huber, Hans-Joachim König, Karsten Ulrich, Martina Lademann, Juergen Darvin, Maxim E
Published in
Experimental dermatology
The routine diagnostic procedure of actinic keratosis (AK) and invasive squamous cell carcinoma (SCC) is a histological examination after taking a biopsy. In the past decades, non-invasive optical methods for skin examination have been developed. Patients with clinical diagnosis of AK or SCC were examined. The morphological criteria were determined...