In this thesis I focus on SCHIZORIZA, a gene involved in tissue specification and cell fate segregation in the Arabidopsis root. Chapter 1 describes asymmetric cell division, Arabidopdis embryo development and root meristem development. In more detail we describe the maintenance of quiescent centre and columella stem cells, the development of groun...
This thesis work aimed at a better understanding of the molecular basis of oriented cell division in plant cell. As, the efficiency of plant morphogenesis depends on oriented cell division, this work should contribute towards a fundamental understanding of the molecular basis of efficient plant morphogenesis. We describe a modelling framework that ...
Abstract Thesis: Circadian rhythms in microalgae production Lenneke de Winter The sun imposes a daily cycle of light and dark on nearly all organisms. The circadian clock evolved to help organisms program their activities at an appropriate time during this daily cycle. For example, UV sensitive processes, like DNA replication, can be scheduled to o...
Keywords: cell division, endoreduplication, cell expansion, cyclin, cyclin dependent kinase, growth theory, systems biology. Okello, R.C.O (2015) Multi-level analysis of the impact of temperature and light on tomato fruit growth. PhD thesis, Wageningen University, Wageningen, The Netherlands, 166 pp, with English and Dutch summaries. Tomato fruit g...
The shape of animal cells is in controlled by a network of filamentous polymers called the cytoskeleton. The two main components of the cytoskeleton are actin filaments and microtubules. These polymers continuously reorganize in order to performed their diverse cellular functions. For example, in processes such as cell migration actin filaments gro...
In De bouwstenen van het leven wordt - ook voor leken - op een toegankelijke wijze een overzicht gegeven van de basale kennis van de biochemie en de moleculaire celbiologie (ook wel Life Sciences genoemd). De wereld van DNA, RNA en eiwitten, van energiemetabolisme tot en met genetica, is door Jan Prinsen en Feike van der Leij op een overzichtelijke...
Plantencellen blijken zich volgens een simpele regel in tweeën te delen; dit gebeurt in het midden, maar wel met een zo klein mogelijk deelvlak. Dit inzicht helpt te verklaren hoe planten hun definitieve vorm krijgen. Opvallend genoeg blijken cellen deze regel ook te overtreden.
In de geneeskunde wordt het gebruik van wiskundige modellen en computersimulaties steeds belangrijker. Zo kan steeds beter voorspeld worden hoe complexe systemen in het lichaam reageren op externe factoren zoals medicijnen. Een toepassing hiervan vindt men in kankeronderzoek. Cellen in het menselijk lichaam kunnen op twee manieren worden aangezet t...
A pool of cells known as stem cells located in the center of the shoot apical meristem (SAM) are responsible to maintain meristematic activity throughout a plants life in order to produce organs. The maintenance of these stem cells is tightly controlled by a complex genetic and hormonal network. Any disruption that leads to the loss of stem cells w...
Keywords: cell division, cell growth, cell endoreduplication, fruit growth, genotype, G×E interaction, model, tomato. Fruit size is a major component of fruit yield and quality of many crops. Variations in fruit size can be tremendous due to genotypic and environmental factors. The mechanisms by which genotype and environment interact to determine ...
