Urbanova, Barbora Soukupova Schwabova, Jaroslava Paulasova Magerova, Hana Jansky, Petr Markova, Hana Vyhnalek, Martin Laczo, Jan Hort, Jakub Tomek, Ales
Published in
Journal of Alzheimer's disease : JAD
Cerebral microangiopathy in Alzheimer's disease (AD) causes chronic hypoperfusion and probably accelerates neurodegenerative changes. We hypothesize microvascular impairment could be present already in mild cognitive impairment (MCI) and can be revealed using transcranial color-coded sonography (TCCS) and the breath-holding maneuver. Three groups o...
Alwatban, Mohammed Truemper, Edward J Al-Rethaia, Abdullah Murman, Daniel L Bashford, Gregory R
Published in
Journal of neuroimaging : official journal of the American Society of Neuroimaging
Cerebrovascular reactivity (CR) is an ideal biomarker to detect cerebrovascular damage. CR can be quantified by measuring changes in cerebral blood flow velocity (CBFV) resulting from a CO2 vasodilatory stimulus, often using the breath-holding index (BHI). In this method, transcranial Doppler (TCD) ultrasound is used to measure CBFV changes in the ...
Prakash, Kiran
Published in
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association
Alwatban, Mohammed Murman, Daniel L Bashford, Greg
Published in
Journal of neuroimaging : official journal of the American Society of Neuroimaging
A substantial overlap exists between declines in cerebral vasoreactivity (CVR) and symptomatic Alzheimer's disease (AD). CVR can be quantified using transcranial Doppler (TCD) measurement of cerebral blood flow velocities (CBFV) in the middle cerebral artery (MCA) with CO2 as a vasodilatory stimulus. The breath-hold acceleration index (BHAI) is a n...
Bian, Ying Wang, Jin-Chun Sun, Feng Sun, Zi-Yi Lin, Yu-Jiao Liu, Yang Zhao, Bin Liu, Li Luo, Xiao-Guang
Published in
Neural Regeneration Research
Many studies have demonstrated that leukoaraiosis is associated with impaired cerebrovascular reserve function. However, the definitive hemodynamic changes that occur in leukoaraiosis are not clear, and there are many controversies. This study aimed to investigate hemodynamic changes in symptomatic leukoaraiosis using transcranial Doppler ultrasono...
Siniscalchi, Antonio La Russa, Antonella Lochner, Piergiorgio Petrone, Alfredo Russo, Bina
Published in
Current medical imaging
Fabry disease (FD) is a rare X-linked multisystem lysosomal storage disease caused by partial or total deficiency of a-galactosidase A (GLA). A progressive involvement of the kidneys, heart, and brain arteries has been reported. Using the transcranial color-coded duplex Doppler (TCCD), we report the case of a Fabry disease (FD) patient with a reduc...
Sabayan, Behnam Sigari, Amirhossein Akhavan Modir, Royya Meyer, Brett C Hemmen, Thomas Meyer, Dawn Shahripour, Reza Bavarsad
Background and purposeCerebral vasomotor reactivity (VMR) is vital for regulating brain blood flow and maintaining neurological function. Impaired cerebral VMR is linked to a higher risk of stroke and poor post-stroke outcomes. This study explores the relationship between statin treatment intensity and VMR in patients with ischemic stroke.MethodsSe...
