de Sousa, Maria Bernardete Cordeiro de Meiroz Grilo, Maria Lara Porpino Galvão-Coelho, Nicole Leite
Published in
Frontiers in Behavioral Neuroscience
Knowledge of the behavioral ecology of marmosets carried out in their natural habitat associated with the advent of a non-invasive technique for measuring steroid hormones in feces has made a significant contribution to understanding their social relationships and sexual strategies. These studies showed that they are mainly monogamous, live in rela...
De Santis, Stefania Scarano, Aurelia Liso, Marina Calabrese, Francesco Maria Verna, Giulio Cavalcanti, Elisabetta Sila, Annamaria Lippolis, Antonio De Angelis, Maria Santino, Angelo
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Published in
Frontiers in Cellular and Infection Microbiology
Neonatal colonization of the gastrointestinal tract depends on mother microbiome, thus mother microbiota dysbiosis is transmitted to the offspring during the delivery and shaped by breastmilk characteristics. Here we used a murine model of UC predisposition (Winnie-/-) to evaluate the effects of maternal diet during pregnancy and lactation. Using h...
Yang, Jing-Rui Xiao, Rui Zhou, Jiang Wang, Lu Wang, Jia-Xing Zhang, Qian Niu, Jian-Xiang Wang, Ze-Feng Yang, Rui-Feng Ren, Jian-Jun
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Published in
Journal of investigative surgery : the official journal of the Academy of Surgical Research
Practical training models can be a viable and effective educational tool that allows surgeons to acquire specific surgical techniques or skills. However, a suitable animal training model for reconstruction after a pancreaticoduodenectomy (PD) has not yet been reported. Therefore, we explored the feasibility and safety of establishing an animal trai...
Li, Cong Shi, Song
Published in
Ear, nose, & throat journal
Administration of d-galactose (d-gal) has been used to create animal models of neurodegenerative diseases, and huperzine A has been used to treat the neurodegenerative diseases such as Alzheimer disease. An animal model of hearing dysfunction was established by administration of d-gal in the rats, and the effect of huperzine A on d-gal-induced abno...
Beale, David J Shah, Rohan Karpe, Avinash V Hillyer, Katie E McAuley, Alexander J Au, Gough G Marsh, Glenn A Vasan, Seshadri S
Published in
Metabolites
Coronavirus disease (COVID-19) is a contagious respiratory disease that is causing significant global morbidity and mortality. Understanding the impact of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection on the host metabolism is still in its infancy but of great importance. Herein, we investigated the metabolic response d...
Rafeek, Rukshan A. M. Sikder, Suchandan Hamlin, Adam S. Andronicos, Nicholas M. McMillan, David J. Sriprakash, Kadaba S. Ketheesan, Natkunam
Published in
Frontiers in Cardiovascular Medicine
The pathogenesis of Acute Rheumatic Fever/Rheumatic Heart Disease (ARF/RHD) and associated neurobehavioral complications including Sydenham's chorea (SC) is complex. Disease complications triggered by Group A streptococcal (GAS) infection are confined to human and determining the early events leading to pathology requires a robust animal model that...
Zhan, Yi Zhu, Hongzhang Li, Wenwen Su, Qiao Liu, Xiao-Lin Qi, Jian
Published in
Journal of investigative surgery : the official journal of the Academy of Surgical Research
This study describes the anatomy of the saphenous artery (SA) perforators in minipigs and the development of a new animal model. First, the anatomic characteristics of the SA and perforators in minipigs were examined after latex-lead oxide perfusion. Subsequently, the right hind limbs of 10 minipigs were used to generate capillary perforator flaps ...
Zhang, Ying Mandemaker, Imke K. Matsumoto, Syota Foreman, Oded Holland, Christopher P. Lloyd, Whitney R. Sugasawa, Kaoru Vermeulen, Wim Marteijn, Jurgen A. Galardy, Paul J.
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Published in
Frontiers in Cell and Developmental Biology
Nucleotide excision repair (NER) is a pathway involved in the repair of a variety of potentially mutagenic lesions that distort the DNA double helix. The ubiquitin E3-ligase complex UV-DDB is required for the recognition and repair of UV-induced cyclobutane pyrimidine dimers (CPDs) lesions through NER. DDB2 directly binds CPDs and subsequently unde...
Petiet, Alexandra
Published in
Frontiers in neuroscience
Parkinson's disease (PD) is a major neurodegenerative disease characterized by massive degeneration of the dopaminergic neurons in the substantia nigra pars compacta, α-synuclein-containing Lewy bodies, and neuroinflammation. Magnetic resonance (MR) imaging plays a crucial role in the diagnosis and monitoring of disease progression and treatment. A...
Carter, Tiffany Qi, Guangyan Wang, Weiqun Nguyen, Annelise Cheng, Nikki Ju, Young Min Lee, Sang Jin Yoo, James J Atala, Anthony Sun, Xiuzhi Susan
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Published in
Advances in wound care
Objective: One of the leading causes of death following traumatic injury is exsanguination. Biological material-based hemostatic agents such as fibrin, thrombin, and albumin have a high risk for causing infection. Synthetic peptide-based hemostatic agents offer an attractive alternative. The objective of this study is to explore the potential of h9...
